Evidence map›Paper›PMID 32033861›Full record

ArticleAcademic radiology2020

Transcatheter Intraarterial Perfusion MRI Approaches to Differentiate Reversibly Electroporated Penumbra From Irreversibly Electroporated Zones in Rabbit Liver.

Liang Pan, Chong Sun, Kang Zhou, Matteo Figini, Bin Wang, Junjie Shangguan, Su Hu, Jia Yang, Wei Xing, Jian Wang and 3 more

Open access · greenAbstract read
In one paragraph

Article in Academic radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Liang PanDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China; Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611.
Chong SunDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611; Department of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Kang ZhouDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611; Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Matteo FiginiDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611.
Bin WangDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611.
Junjie ShangguanDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611.
Su HuDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611; Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Jia YangDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611.
Wei XingDepartment of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Jian WangDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611; Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing, China.
Yury VelichkoDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611.
Vahid YaghmaiDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611.
Zhuoli ZhangDepartment of Radiology, Feinberg School of Medicine, Northwestern University, 737 N. Michigan Ave, 16th Floor, Chicago, IL 60611. Electronic address: zhuoli-zhang@northwestern.edu.
Northwestern University · USQingdao University · CNSoochow University · CN

Funding

MRI-Guided Dendritic-Cell-Based Vaccine Immunotherapy for Pancreatic CancerR01CA209886 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vahid Yaghmai, Zhuoli Zhang · 2016 to 2026
$3.3M
Image-guided Interventional Combination Liver Cancer ImmunotherapyR01CA241532 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI YAGHMAI, VAHID, ZHANG, ZHUOLI · 2020 to 2024
$1.8M
MRI-Guided Irreversible Electroporation Ablation for Liver TumorsR01CA196967 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZHANG, ZHUOLI · 2015 to 2018
$1.4M
NCI NIH HHS R01 CA196967NCI NIH HHS R01 CA209886NCI NIH HHS R01 CA241532
6 · The paper itself

Abstract

RATIONALE AND

objectivesTo investigate whether transcatheter intraarterial perfusion (TRIP) magnetic resonance imaging (MRI) can differentiate reversible electroporation (RE) zones from irreversible electroporation (IRE) zones immediately after IRE procedure in the rabbit liver. MATERIALS AND

methodsAll studies were approved by the institutional animal care and use committee and performed in accordance with institutional guidelines. A total of 13 healthy New Zealand White rabbits were used. After selective catheterization of the hepatic artery under X-ray fluoroscopy, we acquired TRIP-MRI at 20 minutes post-IRE using 3 mL of 5% intraarterial gadopentetate dimeglumine. Semi-quantitative (peak enhancement, PE; time to peak, TTP; wash-in slope, WIS; areas under the time-intensity curve, AUT, over 30, 60, 90, 120, 150, and 180 seconds after the initiation of enhancement) and quantitative (K

resultsPE, AUT

conclusionAUT

Indexed as

Liver NeoplasmsMagnetic Resonance AngiographyAnimalsGadolinium DTPAHepatic ArteryRabbitsGadolinium DTPAIrreversible electroporationLiverRabbitReversible electroporationTranscatheter intraarterial perfusion MRI

Identifiers

PMID32033861
PMCPMC9945946
OpenAlexW3004901460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.