Evidence map›Paper›PMID 32033828›Full record

ReviewSeminars in cell & developmental biology2020

Cellular evasion strategies of Helicobacter pylori in regulating its intracellular fate.

Wei Yang Sit, Yu-An Chen, Yu-Lun Chen, Chih-Ho Lai, Wen-Ching Wang

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Internalization ofAnnals of medicine · 2026
    Review
  2. Article
  3. Autophagy andFrontiers in cellular and infection microbiology · 2026
    Review
  4. Pathogenicity ofWorld journal of clinical oncology · 2025
    Review
  5. Article
  6. Article
  7. Progranulin inhibits autophagy to facilitate intracellular colonization ofFrontiers in cellular and infection microbiology · 2024
    Article
  8. Review
  9. Article
  10. International journal of molecular sciences · 2022
    Review
  11. Host Cell Antimicrobial Responses againstInternational journal of molecular sciences · 2022
    Review
  12. Frontiers in microbiology · 2022
    Review
  13. Gut CommensalFrontiers in immunology · 2022
    Article
  14. Review
  15. Virulence · 2021
    Article
  16. World journal of gastroenterology · 2021
    Article
  17. Article
  18. Article
  19. Clinical Strains ofFrontiers in pharmacology · 2021
    Article
  20. Frontiers in cell and developmental biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Wei Yang SitBiomedical Science and Engineering Center, National Tsing Hua University, Hsinchu, Taiwan; Institute of Molecular and Cellular Biology & Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan.
Yu-An ChenDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA; Department of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan.
Yu-Lun ChenBiomedical Science and Engineering Center, National Tsing Hua University, Hsinchu, Taiwan; Institute of Molecular and Cellular Biology & Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan.
Chih-Ho LaiDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan; Department of Microbiology, School of Medicine, China Medical University, Taichung, Taiwan; Department of Nursing, Asia University, Taichung, Taiwan; Molecular Infectious Disease Research Center, Department of Pediatrics, Chang Gung Memorial Hospital, Linkuo, Taiwan. Electronic address: chlai@mail.cgu.edu.tw.
Wen-Ching WangBiomedical Science and Engineering Center, National Tsing Hua University, Hsinchu, Taiwan; Institute of Molecular and Cellular Biology & Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan. Electronic address: wcwang@life.nthu.edu.tw.
National Tsing Hua University · TWChina Medical University · TWThe University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori colonizes human stomach mucosa and its infection causes gastrointestinal diseases with variable severity. Bacterial infection stimulates autophagy, which is a part of innate immunity used to eliminate intracellular pathogens. Several intracellular bacteria have evolved multipronged strategies to circumvent this conserved system and thereby enhance their chance of intracellular survival. Nonetheless, studies on H. pylori have produced inconsistent results, showing either elevated or reduced clearance efficiency of intracellular bacteria through autophagy. In this review, we summarize recent studies on the mechanisms involved in autophagy induced by H. pylori and the fate of intracellular bacteria.

Indexed as

Gastric MucosaHelicobacter pyloriHost-Pathogen InteractionsHumansImmune EvasionAutophagyHelicobacter pyloriIntracellular survivalVirulence factor

Identifiers

PMID32033828
PMCPMC7102552
OpenAlexW3004741199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.