ArticleTrends in pharmacological sciences2020
DELs Inside Cells.
Article in Trends in pharmacological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
DNA-encoded libraries (DELs) comprise large numbers of small molecules, each of which is conjugated to an encoding DNA. Krusemark and colleagues recently described a method to introduce DELs into living cells and recover conjugates that bind to an intracellular target. This proof-of-principle study suggests that it may be feasible to screen DELs against protein targets in their native environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.