Evidence map›Paper›PMID 32033621›Full record

ArticleBMC research notes2020

Staphylococcus aureus pigmentation is not controlled by Hfq.

Wenfeng Liu, Pierre Boudry, Chantal Bohn, Philippe Bouloc

Abstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. CcpA promotesmLife · 2025
    Article
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  3. Article
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  5. Article
  6. 6S RNA-Dependent Susceptibility to RNA Polymerase Inhibitors.Antimicrobial agents and chemotherapy · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenfeng LiuUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.ORCID http://orcid.org/0000-0003-0747-1852
Pierre BoudryUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.
Chantal BohnUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.ORCID http://orcid.org/0000-0003-1569-9072
Philippe BoulocUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France. philippe.bouloc@cnrs.fr.ORCID http://orcid.org/0000-0003-4601-3387

Funding

Agence Nationale pour la Recherche (ANR) ANR-15-CE12-0003-01Fondation pour la Recherche Médicale (FRM) DBF20160635724
6 · The paper itself

Abstract

objectiveThe golden color of Staphylococcus aureus is due to the synthesis of carotenoid pigments. In Gram-negative bacteria, Hfq is a global posttranscriptional regulator, but its function in S. aureus remains obscure. The absence of Hfq in S. aureus was reported to correlate with production of carotenoid pigment leading to the conclusion that Hfq was a negative regulator of the yellow color. However, we reported the construction of hfq mutants in several S. aureus strains and never noticed any color change; we therefore revisited the question of Hfq implication in S. aureus pigmentation.

resultsThe absence or accumulation of Hfq does not affect S. aureus pigmentation.

Indexed as

Gene Expression Regulation, BacterialHost Factor 1 ProteinPigmentationStaphylococcus aureusHost Factor 1 ProteinHfqPigmentationRegulationStaphylococcus aureusStaphyloxanthin

Identifiers

PMID32033621
PMCPMC7007678

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.