Evidence map›Paper›PMID 32033574›Full record

ArticleRadiation oncology (London, England)2020

Accuracy of automatic deformable structure propagation for high-field MRI guided prostate radiotherapy.

Rasmus Lübeck Christiansen, Lars Dysager, Anders Smedegaard Bertelsen, Olfred Hansen, Carsten Brink, Uffe Bernchou

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Clinical rationale forPhysics and imaging in radiation oncology · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rasmus Lübeck ChristiansenDepartment of Clinical Research, University of Southern Denmark, Winsløwparken 19 3. Sal, 5000, Odense C, Denmark. rasmus.lubeck.christiansen@rsyd.dk.ORCID http://orcid.org/0000-0003-3254-5075
Lars DysagerDepartment of Oncology, Odense University Hospital, Kløvervænget 19 Indgang 85 Pavillion, 1. sal, 5000, Odense C, Denmark.
Anders Smedegaard BertelsenLaboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Kløvervænget 19, Indgang 85, Pavillion, Stuen, 5000, Odense C, Denmark.
Olfred HansenDepartment of Clinical Research, University of Southern Denmark, Winsløwparken 19 3. Sal, 5000, Odense C, Denmark.
Carsten BrinkDepartment of Clinical Research, University of Southern Denmark, Winsløwparken 19 3. Sal, 5000, Odense C, Denmark.
Uffe BernchouDepartment of Clinical Research, University of Southern Denmark, Winsløwparken 19 3. Sal, 5000, Odense C, Denmark.

Funding

Odense Universitetshospital PhD scholarshipSyddansk Universitet Faculty Scholarship
6 · The paper itself

Abstract

backgroundIn this study we have evaluated the accuracy of automatic, deformable structure propagation from planning CT and MR scans for daily online plan adaptation for MR linac (MRL) treatment, which is an important element to minimize re-planning time and reduce the risk of misrepresenting the target due to this time pressure.

methodsFor 12 high-risk prostate cancer patients treated to the prostate and pelvic lymph nodes, target structures and organs at risk were delineated on both planning MR and CT scans and propagated using deformable registration to three T2 weighted MR scans acquired during the treatment course. Generated structures were evaluated against manual delineations on the repeated scans using intra-observer variation obtained on the planning MR as ground truth.

resultsMR-to-MR propagated structures had significant less median surface distance and larger Dice similarity index compared to CT-MR propagation. The MR-MR propagation uncertainty was similar in magnitude to the intra-observer variation. Visual inspection of the deformed structures revealed that small anatomical differences between organs in source and destination image sets were generally well accounted for while large differences were not.

conclusionBoth CT and MR based propagations require manual editing, but the current results show that MR-to-MR propagated structures require fewer corrections for high risk prostate cancer patients treated at a high-field MRL.

Indexed as

AlgorithmsPhantoms, ImagingHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleObserver VariationOrgans at RiskPelvisProstatic NeoplasmsRadiographic Image Interpretation, Computer-AssistedRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedComputed tomographyDeformable image registrationMagnetic resonanceMR-linacProstate cancerRadiotherapyTreatment precision

Identifiers

PMID32033574
PMCPMC7007657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.