Evidence map›Paper›PMID 32033548›Full record

ArticleBMC musculoskeletal disorders2020

The value of dynamic MRI in the treatment of cervical spondylotic myelopathy: a protocol for a prospective randomized clinical trial.

Nanfang Xu, Youyu Zhang, Guangjin Zhou, Qiang Zhao, Shaobo Wang

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nanfang XuDepartment of Orthopaedics, Peking University Third Hospital, Beijing, People's Republic of China.
Youyu ZhangDepartment of Orthopaedics, Peking University Third Hospital, Beijing, People's Republic of China.
Guangjin ZhouDepartment of Radiology, Peking University Third Hospital, Beijing, People's Republic of China.
Qiang ZhaoDepartment of Radiology, Peking University Third Hospital, Beijing, People's Republic of China.
Shaobo WangDepartment of Orthopaedics, Peking University Third Hospital, Beijing, People's Republic of China. Puthwangshaobo@163.com.ORCID http://orcid.org/0000-0002-6000-2548
Peking University · CN

Funding

Beijing Municipal Science and Technology Project Z161100000116096
6 · The paper itself

Abstract

backgroundCervical spondylotic myelopathy (CSM) is the most severe type of cervical spondylosis and the most common cause of spinal cord dysfunction among adults over 55 years old. MRI plays an important role in the diagnosis and evaluation of CSM, which can directly demonstrate the correlation between disc, spinal cord, posterior structures and abnormal signal in spinal cord. Static MRI can only show the static and neutral position of spinal cord, which is not enough to understand the pathogenesis of CSM. Dynamic MRI demonstrating the extension and flexion position of spinal cord can be a better tool for the treatment of CSM, especially the surgical decision making.

methodA total of 180 CSM patients who have indications for surgery will be recruited in outpatient of Peking University Third Hospital and assigned to three groups (Group A, B and C) based on their static MRI after consent. Group A (incomplete dura compression) means the signal of cerebral spinal fluid (CSF) is still visible. Group B (complete dura compression) means no CSF signal and no shape change of spinal cord. Group C (spinal cord compression) means shape change of spinal cord. Two surgical plans will be made for each participant by one professional surgeon according to the static MRI and dynamic MRI respectively and we will randomly choose one to perform via a random number system. Follow-up will be maintained at 3, 6, and 12 months after surgery through outpatient or telephone interview, including mJOA score, 10-s G&R (grip and release) and 10-s step test, SF-36 score, radiographic examination and complications. Finally, data collection and statistical analysis will be finished by researchers who are blinded to recruitment and treatment. DISCUSSION: This study will help us to explore the indication of dynamic MRI and the value of dynamic MRI in the treatment of CSM, especially the surgical decision making. Dynamic MRI can be a useful tool in the treatment of CSM patients.

trial registrationChiCTR1900023014. Registered on May 7th, 2019.

Indexed as

Magnetic Resonance ImagingCervical VertebraeClinical Decision-MakingDiskectomyFemaleFollow-Up StudiesHumansIntervertebral DiscMaleMiddle AgedPostoperative ComplicationsPreoperative PeriodProspective StudiesRandomized Controlled Trials as TopicSpinal CordSpinal Cord CompressionCervical spondylotic myelopathy (CSM)Dynamic magnetic resonance image (dMRI)Surgical treatment

Identifiers

PMID32033548
PMCPMC7007666
OpenAlexW3007715264

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.