Evidence map›Paper›PMID 32033532›Full record

Trial reportBMC geriatrics2020

Augmented exercise in hospital improves physical performance and reduces negative post hospitalization events: a randomized controlled trial.

Ruth McCullagh, Eimear O'Connell, Sarah O'Meara, Darren Dahly, Eilis O'Reilly, Kieran O'Connor, N Frances Horgan, Suzanne Timmons

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02463864 nacompletednot on this map

A Randomised Controlled Trial to Measure the Effects of Twice-Daily Individual, Targeted, Strengthening, Balance and Endurance Exercise Sessions on Mobility, Quality of Life and Healthcare Utilisation for Frail Older Medical In-patients

TypeinterventionalSponsorUniversity College CorkRan2015 to 2017Enrolled190ConditionsFrail Older AdultsArmsIntervention exercise, Sham Exercise
NCT06820021 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effects of a Strength-based Tailored-Exercise Program at Home (STEP@Home) on Health Outcomes of Geriatric Patients at Risk of Hospitalization-associated Functional Decline: A Sequential Mixed-method Study

TypeinterventionalSponsorThe University of Hong KongRan2025 to 2030Enrolled256ConditionsFrailty, GeriatricsArmsStrength-based Tailored-Exercise Program at Home (STEP@Home), Physical activity education
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  4. Exercise for acutely hospitalised older medical patients.The Cochrane database of systematic reviews · 2022
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  8. Effect of Exercise Training on Prognosis in Community-acquired Pneumonia: A Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ruth McCullaghCentre for Gerontology & Rehabilitation, University College Cork, Cork, Ireland. r.mccullagh@ucc.ie.ORCID 0000-0002-6489-183X
Eimear O'ConnellPhysiotherapy Department, Mercy University Hospital, Cork, Ireland.
Sarah O'MearaClinical Research Facility, Mercy University Hospital, Cork, Ireland.
Darren DahlySchool of Public Health, University College Cork, Cork, Ireland.
Eilis O'ReillySchool of Public Health, University College Cork, Cork, Ireland.
Kieran O'ConnorDepartment of Geriatric Medicine, Mercy University Hospital, Cork, Ireland.
N Frances HorganSchool of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Ireland.
Suzanne TimmonsCentre for Gerontology & Rehabilitation, University College Cork, Cork, Ireland.
University College Cork · IEMercy University Hospital · IERoyal College of Surgeons in Ireland · IE

Funding

Health Research Board HPF 451 2013
6 · The paper itself

Abstract

backgroundTo measure the effects of an augmented prescribed exercise programme versus usual care, on physical performance, quality of life and healthcare utilisation for frail older medical patients in the acute setting.

methodsThis was a parallel single-blinded randomised controlled trial. Within 2 days of admission, older medical inpatients with an anticipated length of stay ≥3 days, needing assistance/aid to walk, were blindly randomly allocated to the intervention or control group. Until discharge, both groups received twice daily, Monday-to-Friday half-hour assisted exercises, assisted by a staff physiotherapist. The intervention group completed tailored strengthening and balance exercises; the control group performed stretching and relaxation exercises. Length of stay was the primary outcome measure. Blindly assessed secondary measures included readmissions within 3 months, and physical performance (Short Physical Performance Battery) and quality of life (EuroQOL-5D-5 L) at discharge and at 3 months. Time-to-event analysis was used to measure differences in length of stay, and regression models were used to measure differences in physical performance, quality of life, adverse events (falls, deaths) and negative events (prolonged hospitalisation, institutionalisation).

resultsOf the 199 patients allocated, 190 patients' (aged 80 ± 7.5 years) data were analysed. Groups were comparable at baseline. In intention-to-treat analysis, length of stay did not differ between groups (HR 1.09 (95% CI, 0.77-1.56) p = 0.6). Physical performance was better in the intervention group at discharge (difference 0.88 (95% CI, 0.20-1.57) p = 0.01), but lost at follow-up (difference 0.45 (95% CI, - 0.43 - 1.33) p = 0.3). An improvement in quality of life was detected at follow-up in the intervention group (difference 0.28 (95% CI, 0.9-0.47) p = 0.004). Overall, fewer negative events occurred in the intervention group (OR 0.46 (95% CI 0.23-0.92) p = 0.03).

conclusionImprovements in physical performance, quality of life and fewer negative events suggest that this intervention is of value to frail medical inpatients. Its effect on length of stay remains unclear.

trial registrationClinicalTrials.gov Identifier: NCT02463864, registered prospectively 26.05.2015.

Indexed as

ExerciseQuality of LifeAgedAged, 80 and overExercise TherapyHospitalizationHospitalsHumansPhysical Functional PerformanceExerciseFrailHospitalisationLength of stayPhysiotherapy

Identifiers

PMID32033532
PMCPMC7007685
OpenAlexW3009175801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.