ArticlePathogens (Basel, Switzerland)2020
Common Structural Patterns in the Maxicircle Divergent Region of Trypanosomatidae.
Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Assembly and Annotation of Kinetoplastid and Diplonemid Mitochondrial Genomes.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Kinetoplast DNA structure, RNA editing patterns and small respiratory Complex I in Trypanosoma musculi.Communications biology · 2025Article
- Comparative mitochondrial genome and transcriptome analyses reveal strain-specific features of RNA editing in Trypanosoma brucei.Nucleic acids research · 2025Article
- Mitochondrial DNA Structure inPathogens (Basel, Switzerland) · 2025Review
- Review
- Comparative maxicircle analysis in Trypanosoma species from the LSRM clade highlights patterns in an underexplored lineage.PloS one · 2025Article
- Blastocrithidia nonstop mitochondrial genome and its expression are remarkably insulated from nuclear codon reassignment.Nucleic acids research · 2024Article
- In silico prediction of the metabolism of Blastocrithidia nonstop, a trypanosomatid with non-canonical genetic code.BMC genomics · 2024Article
- A phased genome assembly of a Colombian Trypanosoma cruzi TcI strain and the evolution of gene families.Scientific reports · 2024Article
- Identification of a unique conserved region from a kinetoplastid genome of Leishmania orientalis (formerly named Leishmania siamensis) strain PCM2 in Thailand.Scientific reports · 2023Article
- Kinetoplast Genome ofTropical medicine and infectious disease · 2023Article
- Identification of a conserved maxicircle and unique minicircles as part of the mitochondrial genome of Leishmania martiniquensis strain PCM3 in Thailand.Parasites & vectors · 2022Article
- Article
- Mitochondrial RNA editing inComputational and structural biotechnology journal · 2022Article
- Maxicircle architecture and evolutionary insights into Trypanosoma cruzi complex.PLoS neglected tropical diseases · 2021Article
- Complete minicircle genome of Leptomonas pyrrhocoris reveals sources of its non-canonical mitochondrial RNA editing events.Nucleic acids research · 2021Article
- The Complete Mitochondrial DNA ofFrontiers in cellular and infection microbiology · 2021Article
- Review
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Maxicircles of all kinetoplastid flagellates are functional analogs of mitochondrial genome of other eukaryotes. They consist of two distinct parts, called the coding region and the divergent region (DR). The DR is composed of highly repetitive sequences and, as such, remains the least explored segment of a trypanosomatid genome. It is extremely difficult to sequence and assemble, that is why very few full length maxicircle sequences were available until now. Using PacBio data, we assembled 17 complete maxicircles from different species of trypanosomatids. Here we present their large-scale comparative analysis and describe common patterns of DR organization in trypanosomatids.
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