ArticleBiomolecules2020
Optimization of Catechin and Proanthocyanidin Recovery from Grape Seeds Using Microwave-Assisted Extraction.
Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
- Study on the characteristics and nutritional properties of germinated highland barley treated by different thermal processing based on quasi-targeted metabolomics.Food chemistry: X · 2026Article
- Optimization of Proanthocyanidin Extraction from Grape Seeds Using Response Surface Methodology and Subsequent Evaluation of Its Antioxidant and Immunomodulatory Capacities.Foods (Basel, Switzerland) · 2026Article
- Microwave-Assisted Extraction of Phenolic Compounds from Cocoa Pod Husk: Process Optimization and Impact of Drying Temperature on Bioactive Recovery.Molecules (Basel, Switzerland) · 2025Article
- Stabilizing effect of green tea extract and epigallocatechin-3-gallate (EGCG) on mast cell : an in vivo study.Inflammopharmacology · 2025Article
- Exploring the extraction, antioxidant activities and its stabilities of peanut skins crude proanthocyanidins extract.Scientific reports · 2025Article
- Synergic Treatment of Plant-Based Antioxidants with Iron Chelators for Iron Overload in Transfusion-Dependent-Thalassemia Patients: A Systematic Review.International journal of hematology-oncology and stem cell research · 2025Review
- Grape Winemaking By-Products: Current Valorization Strategies and Their Value as Source of Tannins with Applications in Food and Feed.Molecules (Basel, Switzerland) · 2025Review
- Article
- Insight into the Phenolic Composition of Cabernet Sauvignon Grapevine Berries During Fermentation-Towards the Application of Winery By-Products for Antibacterial Purposes.Antibiotics (Basel, Switzerland) · 2025Article
- The biological functions of proanthocyanidin and its application in pig production.Frontiers in veterinary science · 2025Review
- Extraction, Isolation and Purification of Catechins and their Applications.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025Review
- Valorisation of Winery By-Products: Revealing the Polyphenolic Profile of Grape Stems and Their Inhibitory Effects on Skin Aging-Enzymes for Cosmetic and Pharmaceutical Applications.Molecules (Basel, Switzerland) · 2024Article
- Valorization of Grape Pomace: A Review of Phenolic Composition, Bioactivity, and Therapeutic Potential.Antioxidants (Basel, Switzerland) · 2024Review
- Antimicrobial Polymer Films with Grape Seed and Skin Extracts for Food Packaging.Microorganisms · 2024Review
- Extraction of (+)-catechin from oak (Heliyon · 2023Article
- A Review on Berry Seeds-A Special Emphasis on Their Chemical Content and Health-Promoting Properties.Nutrients · 2023Review
- Phenolic Fraction from Peanut (Food and bioprocess technology · 2023Review
- Multiple response optimizations on the leached-spray-dried bancha green tea towards healthy ageing.Scientific reports · 2022Article
- Microwave-Assisted Water Extraction of Aspen (Plants (Basel, Switzerland) · 2022Article
- Optimization of the Extraction of Proanthocyanidins from Grape Seeds Using Ultrasonication-Assisted Aqueous Ethanol and Evaluation of Anti-Steatosis Activity In Vitro.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Grape seed extract (GSE) is a rich source of condensed flavonoid tannins, also called proanthocyanidins (PACs). The high molecular weight of polymeric PAC limits their biological activity due to poor bioavailability. The present study was undertaken to explore the potential applicability of microwave-assisted extraction (MAE) to convert GSE-PAC into monomeric catechins. A central composite design (CCD) was used to optimize the processing conditions for the MAE. The maximum total yield of monomeric catechins (catechin, epicatechin, and epicatechin gallate) and PAC were 8.2 mg/g dry weight (DW) and 56.4 mg catechin equivalence (CE)/g DW, respectively. The optimized MAE condition was 94% ethanol, 170 °C temperature, and a duration of 55 min. Compared to the results for PACs extracted via conventional extraction (Con) (94% ethanol; shaking at 25 °C for 55 min), MAE yielded 3.9-fold more monomeric catechins and 5.5-fold more PACs. The MAE showed higher antioxidant capacity and α-glucosidase inhibitory activity than that of the conventional extract, suggesting the potential use of the MAE products of grape seeds as a functional food ingredient and nutraceutical.
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Registered trials
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