Evidence map›Paper›PMID 32033365›Full record

ReviewJournal of clinical medicine2020

Curcumin's Nanomedicine Formulations for Therapeutic Application in Neurological Diseases.

Bahare Salehi, Daniela Calina, Anca Oana Docea, Niranjan Koirala, Sushant Aryal, Domenico Lombardo, Luigi Pasqua, Yasaman Taheri, Carla Marina Salgado Castillo, Miquel Martorell and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 1 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 1 synthesis or guideline pooled it, 185 citations in OpenAlex.

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  6. Curcumin-Piperine Self-Nanoemulsifying Delivery inPharmaceuticals (Basel, Switzerland) · 2025
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 8 countries.

Bahare SalehiStudent Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran.
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Anca Oana DoceaDepartment of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Niranjan KoiralaDepartment of Natural Products Research, Dr. Koirala Research Institute for Biotechnology and Biodiversity, Kathmandu 44600, Nepal.
Sushant AryalDepartment of Natural Products Research, Dr. Koirala Research Institute for Biotechnology and Biodiversity, Kathmandu 44600, Nepal.
Domenico LombardoItalian National Research Council, Rome (CNR), 98158 Messina, Italy.
Luigi PasquaDepartment of Environmental and Chemical Engineering, University of Calabria, 87036 Rende (CS), Italy.
Yasaman TaheriPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran.
Carla Marina Salgado CastilloFacultad de Medicina, Universidad del Azuay, 14-008 Cuenca, Ecuador.
Miquel MartorellDepartment of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepcion 4070386, Chile.
Natália MartinsFaculty of Medicine, University of Porto, Alameda Prof. HernâniMonteiro, 4200-319 Porto, Portugal.
Marcello IritiDepartment of Agricultural and Environmental Sciences, Milan State University, 20133 Milan, Italy.
Hafiz Ansar Rasul SuleriaDepartment of Agriculture and Food Systems, The University of Melbourne, Melbourne 3010, Australia.
Javad Sharifi-RadZabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol 61615-585, Iran.
B.P. Koirala Institute of Health Sciences · NPUniversity of Medicine and Pharmacy of Craiova · ROBam University of Medical Sciences · IRNational Research Council · ITShahid Beheshti University of Medical Sciences · IRThe University of Melbourne · AUUniversidad del Azuay · ECUniversidade do Porto · PTUniversity of Calabria · ITUniversity of Concepción · CLUniversity of Milan · ITZabol University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain is the body's control center, so when a disease affects it, the outcomes are devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases that cause a large number of human deaths worldwide. Curcumin has demonstrated beneficial effects on brain health through several mechanisms such as antioxidant, amyloid β-binding, anti-inflammatory, tau inhibition, metal chelation, neurogenesis activity, and synaptogenesis promotion. The therapeutic limitation of curcumin is its bioavailability, and to address this problem, new nanoformulations are being developed. The present review aims to summarize the general bioactivity of curcumin in neurological disorders, how functional molecules are extracted, and the different types of nanoformulations available.

Indexed as

curcuminliposomesnanocarriersnanocurcuminneurological disorders

Identifiers

PMID32033365
PMCPMC7074182
OpenAlexW3004954692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.