Evidence map›Paper›PMID 32033312›Full record

Trial reportNutrients2020

Oropharyngeal Colostrum Positively Modulates the Inflammatory Response in Preterm Neonates.

Estefanía Martín-Álvarez, Javier Diaz-Castro, Manuela Peña-Caballero, Laura Serrano-López, Jorge Moreno-Fernández, Belen Sánchez-Martínez, Francisca Martín-Peregrina, Mercedes Alonso-Moya, José Maldonado-Lozano, Jose A Hurtado-Suazo and 1 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. [Effect of colostrum oral immune therapy on the the clinical outcomes in very low birth weight infants: a Meta analysis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Estefanía Martín-ÁlvarezUnit of Neonatology, Pediatric Service, Hospital Universitario Materno-Infantil Virgen de las Nieves, 18014 Granada, Spain.
Javier Diaz-CastroDepartment of Physiology, University of Granada, 18071 Granada, Spain.ORCID 0000-0003-3659-1757
Manuela Peña-CaballeroUnit of Neonatology, Pediatric Service, Hospital Universitario Materno-Infantil Virgen de las Nieves, 18014 Granada, Spain.
Laura Serrano-LópezUnit of Neonatology, Pediatric Service, Hospital Universitario Materno-Infantil Virgen de las Nieves, 18014 Granada, Spain.
Jorge Moreno-FernándezDepartment of Physiology, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-9690-7851
Belen Sánchez-MartínezUnit of Neonatology, Pediatric Service, Hospital Universitario Materno-Infantil Virgen de las Nieves, 18014 Granada, Spain.
Francisca Martín-PeregrinaUnit of Neonatology, Pediatric Service, Hospital Universitario Materno-Infantil Virgen de las Nieves, 18014 Granada, Spain.
Mercedes Alonso-MoyaUnit of Neonatology, Pediatric Service, Hospital Universitario Materno-Infantil Virgen de las Nieves, 18014 Granada, Spain.
José Maldonado-LozanoPediatrics Department, Virgen de las Nieves University Hospital, University of Granada, 18071 Granada, Spain.
Jose A Hurtado-SuazoUnit of Neonatology, Pediatric Service, Hospital Universitario Materno-Infantil Virgen de las Nieves, 18014 Granada, Spain.
Julio J OchoaDepartment of Physiology, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-8976-6296
Hospital Universitario Virgen de las Nieves · ESUniversidad de Granada · ES

Funding

Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía PI-0374-2014
6 · The paper itself

Abstract

During the first days of life, premature infants have physiological difficulties swallowing, thereby missing out on the benefits of breastfeeding. The aim of this study is to assess the effects of oropharyngeal mother's milk administration in the inflammatory signaling of extremely premature infants. Neonates (

Indexed as

BiomarkersColostrumCytokinesEnteral NutritionFemaleHumansInfant, Extremely PrematureInfant, NewbornInfant, Premature, DiseasesInflammationMilk, HumanPregnancyTreatment OutcomeBiomarkersCytokinesclinical outcomescolostrum administrationinflammationpremature neonates

Identifiers

PMID32033312
PMCPMC7071247
OpenAlexW3004590369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.