Evidence map›Paper›PMID 32033281›Full record

ArticleMolecules (Basel, Switzerland)2020

New Potent 5α- Reductase and Aromatase Inhibitors Derived from 1,2,3-Triazole Derivative.

Mohamed El-Naggar, Amira S Abd El-All, Shweekar I A El-Naem, Mohamed M Abdalla, Huda R M Rashdan

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Recent Advances in Therapeutic Potential of Dual-Acting Aromatase/COX-2.Anti-cancer agents in medicinal chemistry · 2026
    Review
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  8. Article
  9. Development of Metal Complexes for Treatment of Coronaviruses.International journal of molecular sciences · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Comparing Machine Learning Models for Aromatase (P450 19A1).Environmental science & technology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mohamed El-NaggarChemistry Department, Faculty of Sciences, University of Sharjah, Sharjah 27272, UAE.
Amira S Abd El-AllChemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Cairo 12622, Egypt.
Shweekar I A El-NaemChemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Cairo 12622, Egypt.
Mohamed M AbdallaResearch and Development Unit, Saco Pharm. Co., 6 October City 11632, Egypt.
Huda R M RashdanChemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Cairo 12622, Egypt.
National Research Centre · EGUniversity of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work describes the utility of pyrazole-4-carbaldehyde

Indexed as

5-alpha Reductase InhibitorsAnimalsAnti-Bacterial AgentsAntineoplastic AgentsAntiviral AgentsAromataseAromatase InhibitorsCholestenone 5 alpha-ReductaseDihydrotestosteroneLetrozoleRatsRats, Sprague-DawleyStructure-Activity RelationshipTestosteroneTriazoles5-alpha Reductase InhibitorsAnti-Bacterial AgentsAntineoplastic AgentsAntiviral AgentsAromataseAromatase InhibitorsCholestenone 5 alpha-ReductaseDihydrotestosteroneLetrozoleTestosteroneTriazoles1,2,3-triazoles5-α reductase inhibitorsaromatase inhibitorshormone-dependent cancer

Identifiers

PMID32033281
PMCPMC7037409
OpenAlexW3004958816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.