Evidence map›Paper›PMID 32033218›Full record

ArticleGenes2020

Whole Genome Sequencing Indicates Heterogeneity of Hyperostotic Disorders in Dogs.

Anna Letko, Fabienne Leuthard, Vidhya Jagannathan, Daniele Corlazzoli, Kaspar Matiasek, Daniela Schweizer, Marjo K Hytönen, Hannes Lohi, Tosso Leeb, Cord Drögemüller

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. The Genetic Architecture of High Bone Mass.Frontiers in endocrinology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Anna LetkoInstitute of Genetics, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Fabienne LeuthardInstitute of Genetics, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Vidhya JagannathanInstitute of Genetics, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Daniele CorlazzoliClinica Veterinaria Roma Sud, 00173 Roma, Italy.
Kaspar MatiasekSection of Clinical & Comparative Neuropathology, Centre for Clinical Veterinary Medicine, Ludwig Maximilians Universität Munich, 80539 Munich, Germany.
Daniela SchweizerDivision of Clinical Radiology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Marjo K HytönenDepartment of Medical and Clinical Genetics, and Department of Veterinary Biosciences, University of Helsinki, 00014 Helsinki, Finland.
Hannes LohiDepartment of Medical and Clinical Genetics, and Department of Veterinary Biosciences, University of Helsinki, 00014 Helsinki, Finland.
Tosso LeebInstitute of Genetics, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Cord DrögemüllerInstitute of Genetics, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
University of Bern · CHUniversity of Helsinki · FILudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Craniomandibular osteopathy (CMO) and calvarial hyperostotic syndrome (CHS) are proliferative, non-neoplastic disorders affecting the skull bones in young dogs. Different forms of these hyperostotic disorders have been described in many dog breeds. However, an incompletely dominant causative variant for CMO affecting splicing of

Indexed as

Genetic VariationGenomeAnimalsDog DiseasesDogsGenetic Diseases, InbornGenomicsGenotypeHyperostosisWhole Genome SequencingCaffey diseasecalvarial hyperostotic syndromeCOL1A1craniomandibular osteopathyinfantile cortical hyperostosisrare diseaseSLC35D1SLC37A2whole-genome sequencing

Identifiers

PMID32033218
PMCPMC7074049
OpenAlexW3005395810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.