Evidence map›Paper›PMID 32033109›Full record

ArticlePathogens (Basel, Switzerland)2020

Map3k14 as a Regulator of Innate and Adaptive Immune Response during Acute Viral Infection.

Thamer A Hamdan, Hilal Bhat, Lamin B Cham, Tom Adomati, Judith Lang, Fanghui Li, Ali Murtaza, Cornelia Hardt, Philipp A Lang, Vikas Duhan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Thamer A HamdanInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Hilal BhatInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Lamin B ChamInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.ORCID 0000-0002-6855-5657
Tom AdomatiInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Judith LangInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.ORCID 0000-0001-5352-106X
Fanghui LiInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Ali MurtazaInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Cornelia HardtInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Philipp A LangDepartment of Molecular Medicine II, Medical Faculty, Heinrich Heine University, Universitätsstrasse 1, 40225 Düsseldorf, Germany.ORCID 0000-0001-5341-0407
Vikas DuhanInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.ORCID 0000-0002-6337-8225
Karl S LangInstitute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
University of Duisburg-Essen · DEHeinrich Heine University Düsseldorf · DEQIMR Berghofer Medical Research Institute · AU

Funding

Deutsche Forschungsgemeinschaft grants LA1419/5-1, LA1419/7-1, LA1558/5-1, and 715 SI1558/3-1
6 · The paper itself

Abstract

The replication of virus in secondary lymphoid organs is crucial for the activation of antigen-presenting cells. Balanced viral replication ensures the sufficient availability of antigens and production of cytokines, and both of which are needed for virus-specific immune activation and viral elimination. Host factors that regulate coordinated viral replication are not fully understood. In the study reported here, we identified

Indexed as

Alymphoplasia micegenome-wide association studylymphocytic choriomeningitis virusmarginal zonevesicular stomatitis virusviral infection

Identifiers

PMID32033109
PMCPMC7168624
OpenAlexW3004470473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.