Evidence map›Paper›PMID 32033039›Full record

ArticleMolecules (Basel, Switzerland)2020

Synthesis of New Cisplatin Derivatives from Bile Acids.

Barbara Seroka, Zenon Łotowski, Agnieszka Hryniewicka, Lucie Rárová, Rafal R Sicinski, Aneta M Tomkiel, Jacek W Morzycki

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Physiology and Physical Chemistry of Bile Acids.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Barbara SerokaFaculty of Chemistry, University of Białystok, K. Ciołkowskiego 1K, 15-245 Białystok, Poland.ORCID 0000-0002-2157-4180
Zenon ŁotowskiFaculty of Chemistry, University of Białystok, K. Ciołkowskiego 1K, 15-245 Białystok, Poland.
Agnieszka HryniewickaFaculty of Chemistry, University of Białystok, K. Ciołkowskiego 1K, 15-245 Białystok, Poland.ORCID 0000-0002-1183-054X
Lucie RárováLaboratory of Growth Regulators, Faculty of Science, Palacký University, and Institute of Experimental Botany of the Czech Academy of Sciences, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic.
Rafal R SicinskiFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
Aneta M TomkielFaculty of Chemistry, University of Białystok, K. Ciołkowskiego 1K, 15-245 Białystok, Poland.
Jacek W MorzyckiFaculty of Chemistry, University of Białystok, K. Ciołkowskiego 1K, 15-245 Białystok, Poland.ORCID 0000-0002-9049-5670
University of Białystok · PLCzech Academy of Sciences, Institute of Experimental Botany · CZUniversity of Warsaw · PL

Funding

European Regional Development Fund CZ.02.1.01/0.0/0.0/16_019/0000868Narodowe Centrum Nauki 2014/15/B/ST5/02129
6 · The paper itself

Abstract

A series of bile acid derived 1,2- and 1,3-diamines as well as their platinum(II) complexes were designed and synthesized in hope to get a highly cytotoxic compound by the combination of two bioactive moieties. All complexes obtained were subjected to cytotoxicity assays in vitro and some hybrid molecules showed an expected activity.

Indexed as

Bile Acids and SaltsCell ProliferationCell SurvivalCisplatinDrug DesignHeLa CellsHumansHuman Umbilical Vein Endothelial CellsInhibitory Concentration 50MCF-7 CellsMolecular StructurePlatinum CompoundsBile Acids and SaltsCisplatinPlatinum Compoundsbile acidscholic aciddeoxycholic acidhyodeoxycholic acidlithocholic acidplatinum(II) complexessteroidal diamines

Identifiers

PMID32033039
PMCPMC7036801
OpenAlexW3005323513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.