ArticleAntibiotics (Basel, Switzerland)2020
Predicting Antimicrobial and Other Cysteine-Rich Peptides in 1267 Plant Transcriptomes.
Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Study Protocol for Genomic Epidemiology Investigation of Intensive Care Unit Patient Colonization by Antimicrobial-Resistant ESKAPE Pathogens.Methods and protocols · 2025Article
- Computational Prediction and Structural Analysis of α-Hairpinins, a Ubiquitous Family of Antimicrobial Peptides, Using the Cysmotif Searcher Pipeline.Antibiotics (Basel, Switzerland) · 2024Article
- Complex of Defense Polypeptides of Wheatgrass (Plants (Basel, Switzerland) · 2024Article
- Plant-Derived Antimicrobials and Their Crucial Role in Combating Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2024Review
- Plant peptides - redefining an area of ribosomally synthesized and post-translationally modified peptides.Natural product reports · 2024Review
- Amaranthus hypochondriacus seeds as a rich source of cysteine rich bioactive peptides.Food chemistry · 2022Article
- Mass Spectrometric Identification of Antimicrobial Peptides from Medicinal Seeds.Molecules (Basel, Switzerland) · 2021Article
- Transcriptomic Analysis of Genes Involved in Plant Defense Response to the Cucumber Green Mottle Mosaic Virus Infection.Life (Basel, Switzerland) · 2021Article
- Synthetic Oligopeptides Mimicking γ-Core Regions of Cysteine-Rich Peptides ofCurrent issues in molecular biology · 2021Article
- Too Hot to Handle: Antibacterial Peptides Identified in Ghost Pepper.Journal of natural products · 2021Article
- Diversity of International High-Risk Clones ofAntibiotics (Basel, Switzerland) · 2021Article
- Proteomic response of Escherichia coli to a membrane lytic and iron chelating truncated Amaranthus tricolor defensin.BMC microbiology · 2021Article
- Multiple Classes of Antimicrobial Peptides inJournal of natural products · 2021Article
- The thionin family of antimicrobial peptides.PloS one · 2021Article
- Discovery of a Beetroot Protease Inhibitor to Identify and Classify Plant-Derived Cystine Knot Peptides.Journal of natural products · 2020Article
- Molecular and Biological Properties of Snakins: The Foremost Cysteine-Rich Plant Host Defense Peptides.Journal of fungi (Basel, Switzerland) · 2020Review
- Isolation of Cysteine-Rich Peptides fromBiomolecules · 2020Article
- Antibacterial Peptides.Antibiotics (Basel, Switzerland) · 2020Article
- Isolation of antimicrobial peptides from different plant sources: Does a general extraction method exist?Plant methods · 2020Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Antimicrobial peptides (AMPs) are a key component of innate immunity in various organisms including bacteria, insects, mammals, and plants. Their mode of action decreases the probability of developing resistance in pathogenic organisms, which makes them a promising object of study. However, molecular biology methods for searching for AMPs are laborious and expensive, especially for plants. Earlier, we developed a computational pipeline for identifying potential AMPs based on the cysteine motifs they usually possess. Since most motifs are too species-specific, a wide-scale screening of novel data is required to maintain the accuracy of searching algorithms. We have performed a search for potential AMPs in 1267 plant transcriptomes using our pipeline. On average, 50-150 peptides were revealed in each transcriptome. The data was verified by a BLASTp search in nr database to confirm peptide functions and by using random nucleotide sequences to estimate the fraction of erroneous predictions. The datasets obtained will be useful both for molecular biologists investigating AMPs in various organisms and for bioinformaticians developing novel algorithms of motif searching in transcriptomic and genomic sequences. The results obtained will represent a good reference point for future investigations in the fields mentioned above.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.