ArticleExperimental eye research2020
Increased endogenous dopamine prevents myopia in mice.
Article in Experimental eye research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Retinal Function in Young Adults Following Topical Application of Levodopa to the Eye.Translational vision science & technology · 2024Trial
- Acute Effects of Oral Caffeine Intake on Human Global-Flash mfERG Responses: A Placebo-Controlled, Double-Masked, Balanced Crossover Study.Investigative ophthalmology & visual science · 2024Trial
- Sleep deprivation exacerbates lens‑induced myopia in association with ERK/NF‑κB pathway activation.Molecular medicine reports · 2026Article
- Scleral Postn Drives Myopia via Promoting Myofibroblast Transdifferentiation.Investigative ophthalmology & visual science · 2026Article
- Light-at-night exposure drives myopia via melanopsin signalling.Science China. Life sciences · 2026Article
- Review
- Light and myopia: a focus on the expanding role of non-visual opsins.Eye and vision (London, England) · 2026Review
- Navigating the Core Challenges of Atropine Therapy in Myopia: A Mechanistic and Clinical Analysis of Dose, Response, and Durability.Journal of ophthalmology · 2026Review
- The interplay between form deprivation and dopamine signaling in regulating the expression of circadian rhythm-related genes in the retina of mice.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- IMI: The Role of Light in Refractive Development and Myopia: Evidence from Animal and Human Studies.Investigative ophthalmology & visual science · 2025Review
- Methylphenidate Inhibits the Development of Myopia by Altering Dopamine and Norepinephrine Reuptake.Investigative ophthalmology & visual science · 2025Article
- Comparative Analysis of Tyrosine Hydroxylase Amacrine Cells in the Mammalian Retina: Distribution and Quantification in Mouse, Rat, Ground Squirrel and Macaque Retinas.International journal of molecular sciences · 2025Article
- Dose-dependent myopia-suppressing effect of 4-phenlybutyric acid eye drops in a mouse myopia model under masked condition.BMC ophthalmology · 2025Article
- Smartwatch-monitored physical activity and myopia in children: a 2-year prospective cohort study.BMC medicine · 2025Article
- The potential role of amino acids in myopia: inspiration from metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2024Review
- Assessment of potential myopia risk factors, including chronotype, in Estonian adolescents: a cross-sectional study.BMC ophthalmology · 2024Article
- Impact of red and blue monochromatic light on the visual system and dopamine pathways in juvenile zebrafish.BMC ophthalmology · 2024Article
- Rodent Models of Retinal Degeneration: From Purified Cells in Culture to Living Animals.Cold Spring Harbor perspectives in medicine · 2024Review
- Changes in Intrinsically Photosensitive Retinal Ganglion Cells, Dopaminergic Amacrine Cells, and Their Connectivity in the Retinas of Lid Suture Myopia.Investigative ophthalmology & visual science · 2024Article
- Loss of ON-Pathway Function in Mice Lacking Lrit3 Decreases Recovery From Lens-Induced Myopia.Investigative ophthalmology & visual science · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Experimental evidence suggests that dopamine (DA) modulates refractive eye growth. We evaluated whether increasing endogenous DA activity using pharmacological or genetic approaches decreased myopia susceptibility in mice. First, we assessed the effects of systemic L-3,4-dihydroxyphenylalanine (L-DOPA) injections on form deprivation myopia (FDM) in C57BL/6 J (WT
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.