Evidence map›Paper›PMID 32032523›Full record

ArticleCell stem cell2020

Human iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts.

Nadia O Abutaleb, George A Truskey

Abstract readComment
In one paragraph

Article in Cell stem cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Bioengineered vascular grafts with a pathogenicScience translational medicine · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nadia O AbutalebDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
George A TruskeyDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA. Electronic address: gtruskey@duke.edu.

Funding

In Vitro Human Tissue-Engineered Blood Vessel Disease Model of ProgeriaR01HL138252 · NHLBI · DUKE UNIVERSITY · PI TRUSKEY, GEORGE A · 2017 to 2025
$4.7M
Vascular, Cardiac, and Lung Alveolar Human Microphysiological Systems for SARS-CoV-2 Drug ScreeningUH3TR002142 · NCATS · DUKE UNIVERSITY · PI TRUSKEY, GEORGE A · 2019 to 2021
$4.0M
NCATS NIH HHS UH3 TR002142NHLBI NIH HHS R01 HL138252
6 · The paper itself

Abstract

Human induced pluripotent stem cells (hiPSCs) provide a potentially unlimited cell source for producing autologous tissue-engineered vascular grafts (TEVGs), which currently suffer from low mechanical strength. In this issue of Cell Stem Cell, Luo et al. (2020) describe optimized culture media and a mechanical stretching regimen to produce hiPSC-derived TEVGs with mechanical behavior similar to that of natural vessels.

Indexed as

Induced Pluripotent Stem CellsBlood Vessel ProsthesisHumansTissue Engineering

Identifiers

PMID32032523
PMCPMC7229643

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.