ArticlePloS one2020
On the usefulness of parental lines GWAS for predicting low heritability traits in tropical maize hybrids.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Optimizing Genomic-Enabled Prediction in Small-Scale Maize Hybrid Breeding Programs: A Roadmap Review.Frontiers in plant science · 2021Pooled it
- Molecular breeding approaches for the improvement of oil content and fatty acid composition in exotic-derived maize germplasm.The New phytologist · 2025Article
- Advancements and Prospects of Genome-Wide Association Studies (GWAS) in Maize.International journal of molecular sciences · 2024Review
- Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing.Genome biology · 2023Article
- Complex traits and candidate genes: estimation of genetic variance components across multiple genetic architectures.G3 (Bethesda, Md.) · 2023Article
- Mapping and Functional Analysis of QTL for Kernel Number per Row in Tropical and Temperate-Tropical Introgression Lines of Maize (Current issues in molecular biology · 2023Article
- Genomic selection for target traits in the Australian lentil breeding program.Frontiers in plant science · 2023Article
- On the usefulness of mock genomes to define heterotic pools, testers, and hybrid predictions in orphan crops.Frontiers in plant science · 2023Article
- Genome-wide association studies of grain yield and quality traits under optimum and low-nitrogen stress in tropical maize (Zea mays L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Genetic mapping and prediction of flowering time and plant height in a maize Stiff Stalk MAGIC population.Genetics · 2022Article
- Population-tailored mock genome enables genomic studies in species without a reference genome.Molecular genetics and genomics : MGG · 2022Article
- Automated Machine Learning: A Case Study of Genomic "Image-Based" Prediction in Maize Hybrids.Frontiers in plant science · 2022Article
- On the genetic architecture in a public tropical maize panel of the symbiosis between corn and plant growth-promoting bacteria aiming to improve plant resilience.Molecular breeding : new strategies in plant improvement · 2021Article
- Genome-wide association mapping in maize: status and prospects.3 Biotech · 2021Review
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4 authors.
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Abstract
Genome-wide association studies (GWAS) is one of the most popular methods of studying the genetic control of traits. This methodology has been intensely performed on inbred genotypes to identify causal variants. Nonetheless, the lack of covariance between the phenotype of inbred lines and their offspring in cross-pollinated species (such as maize) raises questions on the applicability of these findings in a hybrid breeding context. To address this topic, we incorporated previously reported parental lines GWAS information into the prediction of a low heritability trait in hybrids. This was done by marker-assisted selection based on significant markers identified in the lines and by genomic prediction having these markers as fixed effects. Additive-dominance GWAS of hybrids, a non-conventional procedure, was also performed for comparison purposes. Our results suggest that incorporating information from parental inbred lines GWAS led to decreases in the predictive ability of hybrids. Correspondingly, inbred lines and hybrids-based GWAS yielded different results. These findings do not invalidate GWAS on inbred lines for selection purposes, but mean that it may not be directly useful for hybrid breeding.
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