ArticlePloS one2020
Association between TSH levels within the reference range and adiposity markers at the baseline of the ELSA-Brasil study.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Neck circumference in Latin America and the Caribbean: A systematic review and meta-analysis.Wellcome open research · 2021Pooled it
- Clinical and metabolic links between hypothyroidism and metabolic syndrome: a review.Frontiers in endocrinology · 2026Review
- Prevalence and associated factors of obesity in patients with major depressive disorder at different ages of onset.European archives of psychiatry and clinical neuroscience · 2025Article
- Clinical features of overweight in acute-phase hospitalised major depressive disorder with comorbid anxiety: a cross-sectional study.BMJ open · 2025Article
- Association of Thyroid Hormones with Basal Metabolism and Body Composition in Women of Reproductive Age.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025Observational
- Relationship between thyroid-stimulating hormone and blood lipids in patients with first-episode depression.BMC psychiatry · 2024Article
- Association between Neck Circumference and Thyroid Disease: Findings of a Nationwide Cross-Sectional Study in Korea.Iranian journal of public health · 2024Article
- Association between High Normal TSH Levels and Obesity in Women with Anti-Thyroid Autoantibodies (ATAs).Journal of clinical medicine · 2022Article
- Causal Association Between Serum Thyrotropin and Obesity: A Bidirectional, Mendelian Randomization Study.The Journal of clinical endocrinology and metabolism · 2021Article
- Environmental Factors Affecting Thyroid-Stimulating Hormone and Thyroid Hormone Levels.International journal of molecular sciences · 2021Review
- No Association between Neck Circumference and Free Triiodothyronine in Euthyroid Men.International journal of endocrinology · 2021Article
- Within-Person Variation in Serum Thyrotropin Concentrations: Main Sources, Potential Underlying Biological Mechanisms, and Clinical Implications.Frontiers in endocrinology · 2021Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe association of thyrotropin (TSH) with overall (body mass index, BMI), visceral (waist circumference and steatosis), and upper subcutaneous (neck circumference, NC) adiposity markers is still controversial, and the aim of this study is to assess these associations in the baseline data of a large cohort from ELSA-Brasil. METHODS AND
findingsThis cross-sectional study included 11,224 participants with normal thyroid function (normal TSH levels). BMI, waist circumference, NC and steatosis, defined by hepatic attenuation (mild or moderate/severe) were the explicative variables. TSH levels were log transformed (logTSH), and multivariate linear regression models were generated to estimate the associations between logTSH and BMI (continuous and categorized), waist circumference, NC, and steatosis after adjusting for sociodemographic characteristics, health behaviors, and comorbidities. The mean age was 51.5±8.9 years, 5,793 (51.6%) participants were women, 21.8% (n = 2,444) were obese, and 15.1% of the sample was TPOAb positive. The TSH levels were significantly higher in the obese group than in the reference group (<25.0 kg/m2). In the multivariable linear regression models, significant associations of logTSH with BMI and obesity were found. LogTSH was associated with waist circumference only among women. NC and steatosis were not related to TSH levels.
conclusionsTSH levels were associated with overall adiposity and obesity. Further studies may elucidate reference levels of TSH according to BMI status.
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