Evidence map›Paper›PMID 32032215›Full record

ArticleJournal of pediatric orthopedics2020

Fassier-Duval Rod Failure: Is It Related to Positioning in the Distal Epiphysis?

Kaley Holmes, Jane Gralla, Christopher Brazell, Patrick Carry, Suhong Tong, Nancy H Miller, Gaia Georgopoulos

Open access · greenAbstract read
In one paragraph

Article in Journal of pediatric orthopedics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  9. Osteogenesis Imperfecta-Who Needs Rodding Surgery?Current osteoporosis reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kaley HolmesMusculoskeletal Research Center, Orthopedics Institute, Children's Hospital Colorado.
Jane GrallaDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO.
Christopher BrazellMusculoskeletal Research Center, Orthopedics Institute, Children's Hospital Colorado.
Patrick CarryMusculoskeletal Research Center, Orthopedics Institute, Children's Hospital Colorado.
Suhong TongDepartment of Biostatistics and Informatics, Colorado School of Public Health.
Nancy H MillerMusculoskeletal Research Center, Orthopedics Institute, Children's Hospital Colorado.
Gaia GeorgopoulosMusculoskeletal Research Center, Orthopedics Institute, Children's Hospital Colorado.
Children's Hospital Colorado · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · US

Funding

Colorado Clinical and Translational Science Institute (KL2)KL2RR025779 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$2.2M
NCRR NIH HHS KL2 RR025779
6 · The paper itself

Abstract

backgroundThe relationship between Fassier-Duval (FD) rod placement and rod failure rates has not previously been quantified.

methodsRetrospective review was conducted on patients with osteogenesis imperfecta treated with FD rods between 2005 and 2017. Age at first surgery, sex, Sillence type of osteogenesis imperfecta, bisphosphonate treatment, location of rod (side of body and specific bone), and dates of surgeries, radiographs, and rod failures were collected. C-arm images determined rod fixation within the distal epiphysis at the time of surgery. C-arm variables included rod deviation (percent deviation from the midline of the distal epiphysis) and anatomical direction of deviation (anterior/posterior and medial/lateral). X-ray images were examined for rod failure, which was defined as bending, pulling out of the physis, protrusion out of the bone, and/or failure to telescope. Cox proportional hazards regression models were used to compare failure rates with location of placement within the distal epiphysis allowing for clustering of the data by side (left or right) and bone (femur or tibia).

resultsThe cohort was 13 patients (11 female individuals and 2 male individuals) with a total of 66 rods and 75 surgeries. Mean time from the first surgery to the last follow-up visit was 8.9 years (SD=5 y). There was a 7% increase in hazard of failure per 1-mm increase in antero-posterior (AP) deviation [hazard ratio (HR), 1.07; 95% confidence interval (CI), 1.01-1.14; P=0.029)]. Similarly, there was a 9% increase in hazard of failure for every 1-mm increase in lateral deviation (HR, 1.09; 95% CI, 1.01-1.18; P=0.019). A 12% increase in hazard of failure per 10% increase in deviation from the midline for both AP and lateral radiograph views was also found, although this was only statistically significant for lateral deviation on the AP radiograph view (HR, 1.12; 95% CI, 1.01-1.25; P=0.030).

conclusionsFD rod placement within the distal epiphysis has significant impact on increasing rod survival. LEVEL OF EVIDENCE: Level III-therapeutic study.

Indexed as

Fractures, BoneOrthopedic ProceduresOsteogenesis ImperfectaProsthesis FittingChildChild, PreschoolEpiphysesEquipment Failure AnalysisFemaleHumansMaleOutcome and Process Assessment, Health CareRadiographyRetrospective StudiesUnited States

Identifiers

PMID32032215
PMCPMC7415471
OpenAlexW3005307619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.