ArticleJournal of the American Chemical Society2020
Triggered Release of Loads from Microcapsule-in-Microcapsule Hydrogel Microcarriers: En-Route to an "Artificial Pancreas".
Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 73 citations in OpenAlex.
- Bioelectrochemically Powered Out-of-Equilibrium Hydrogels Enable Feedback-Regulated Functions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Nanohydrogels for Diabetic Wound Healing: Mechanisms, Applications, and Future Perspectives.International journal of nanomedicine · 2026Review
- Material-driven glucose responsiveness in insulin delivery systems: carrier selection and performance.Frontiers in endocrinology · 2026Review
- Dual-Drug Delivery Systems Using Hydrogel-Nanoparticle Composites: Recent Advances and Key Applications.Gels (Basel, Switzerland) · 2025Review
- MercuryMikrochimica acta · 2024Article
- Stimuli-Responsive DNA-Based Hydrogels on Surfaces for Switchable Bioelectrocatalysis and Controlled Release of Loads.ACS applied materials & interfaces · 2023Article
- Ester Bonds for Modulation of the Mechanical Properties of Protein Hydrogels.International journal of molecular sciences · 2023Article
- PhotocleavableChemical reviews · 2023Review
- Design and application of stimuli-responsive DNA hydrogels: A review.Materials today. Bio · 2022Review
- Topologically switchable and gated transcription machinery.Chemical science · 2022Article
- Biocatalytic cascades and intercommunicated biocatalytic cascades in microcapsule systems.Chemical science · 2022Article
- Increasing Access to Care for Transgender/Gender Diverse Youth Using Telehealth: A Quality Improvement Project.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2022Article
- Biomaterials to enhance stem cell transplantation.Cell stem cell · 2022Review
- Article
- SiRNA-templated 3D framework nucleic acids for chemotactic recognition, and programmable and visualized precise delivery for synergistic cancer therapy.Chemical science · 2021Article
- Aptamer-modified DNA tetrahedra-gated metal-organic framework nanoparticle carriers for enhanced chemotherapy or photodynamic therapy.Chemical science · 2021Article
- DNAzyme- and light-induced dissipative and gated DNA networks.Chemical science · 2021Article
- Aptamer-Functionalized Hybrid Nanostructures for Sensing, Drug Delivery, Catalysis and Mechanical Applications.International journal of molecular sciences · 2021Review
- A DNA nanopillar as a scaffold to regulate the ratio and distance of mimic enzymes for an efficient cascade catalytic platform.Chemical science · 2020Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A method to assemble stimuli-responsive nucleic acid-based hydrogel-stabilized microcapsule-in-microcapsule systems is introduced. An inner aqueous compartment stabilized by a stimuli-responsive hydrogel-layer (∼150 nm) provides the inner microcapsule (diameter ∼2.5 μm). The inner microcapsule is separated from an outer aqueous compartment stabilized by an outer stimuli-responsive hydrogel layer (thickness of ∼150 nm) that yields the microcapsule-in-microcapsule system. Different loads, e.g., tetramethyl rhodamine-dextran (TMR-D) and CdSe/ZnS quantum dots (QDs), are loaded in the inner and outer aqueous compartments. The hydrogel layers exist in a higher stiffness state that prevents inter-reservoir or leakage of the loads from the respective aqueous compartments. Subjecting the inner hydrogel layer to Zn
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.