Evidence map›Paper›PMID 32031719›Full record

ArticleClinical transplantation2020

Validating patient prioritization in the 2018 Revised United Network for Organ Sharing Heart Allocation System: A single-center experience.

Aditi Nayak, Tiffany Dong, Yi-An Ko, Neile Chesnut, Ann Pekarek, Robert T Cole, Kunal Bhatt, Divya Gupta, Michael A Burke, S Raja Laskar and 4 more

Open access · greenAbstract read
In one paragraph

Article in Clinical transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Aditi NayakEmory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-6986-0987
Tiffany DongEmory University School of Medicine, Atlanta, GA, USA.
Yi-An KoEmory Rollins School of Public Health, Atlanta, GA, USA.
Neile ChesnutEmory University School of Medicine, Atlanta, GA, USA.
Ann PekarekEmory University School of Medicine, Atlanta, GA, USA.
Robert T ColeInova Fairfax Hospital, Falls Church, VA, USA.
Kunal BhattEmory University School of Medicine, Atlanta, GA, USA.
Divya GuptaEmory University School of Medicine, Atlanta, GA, USA.
Michael A BurkeEmory University School of Medicine, Atlanta, GA, USA.
S Raja LaskarEmory University School of Medicine, Atlanta, GA, USA.
Tamer AttiaEmory University School of Medicine, Atlanta, GA, USA.
Andrew L SmithEmory University School of Medicine, Atlanta, GA, USA.
J David VegaEmory University School of Medicine, Atlanta, GA, USA.
Alanna A MorrisEmory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-8033-3707
Emory University · USInova Fairfax Hospital · US

Funding

Metabolomics, Oxidative Stress, and Vascular Function in Heart Failure PatientsK23HL124287 · NHLBI · EMORY UNIVERSITY · PI MORRIS, ALANNA AMYRE · 2015 to 2019
$804k
NHLBI NIH HHS K23 HL124287
6 · The paper itself

Abstract

The 2018 Revised United Network for Organ Sharing Heart Allocation System (HAS) was proposed to reclassify status 1A candidates into groups of decreasing acuity; however, it does not take into account factors such as body mass index (BMI) and blood group which influence waitlist (WL) outcomes. We sought to validate patient prioritization in the new HAS at our center. We retrospectively evaluated patients listed for heart transplantation (n = 214) at Emory University Hospital from 2011 to 2017. Patients were reclassified into the 6-tier HAS. Multistate modeling and competing risk analysis were used to compare outcomes of transplantation and WL death/deterioration between new tiers. Additionally, a stratified sensitivity analysis by BMI and blood group was performed. Compared with tier 4 patients, there was progressively increasing hazard of WL death/deterioration in tier 3 (HR: 2.52, 95% CI: 1.37-4.63, P = .003) and tier 2 (HR: 5.03, 95% CI: 1.99-12.70, P < .001), without a difference in transplantation outcome. When stratified by BMI and blood group, this hierarchical association was not valid in patients with BMI ≥30 kg/m

Indexed as

Heart TransplantationTissue and Organ ProcurementBody Mass IndexHumansRetrospective StudiesRisk AssessmentUnited StatesWaiting Listsheart allocationheart transplantmortality

Identifiers

PMID32031719
PMCPMC7117873
OpenAlexW3005201842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.