Evidence map›Paper›PMID 32031542›Full record

ArticleTherapeutic advances in neurological disorders2020

Randomized controlled trial combining constraint-induced movement therapy and action-observation training in unilateral cerebral palsy: clinical effects and influencing factors of treatment response.

Cristina Simon-Martinez, Lisa Mailleux, Jasmine Hoskens, Els Ortibus, Ellen Jaspers, Nicole Wenderoth, Giuseppina Sgandurra, Giovanni Cioni, Guy Molenaers, Katrijn Klingels and 1 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in neurological disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03256357 (Effectiveness of Intensive Upper Limb Training Combining Constraint-Induced Movement Therapy and Action Observation Training in Children With Unilateral Cerebral Palsy), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03256357 nacompletednot on this map

Effectiveness of Intensive Upper Limb Training Combining Constraint-Induced Movement Therapy and Action Observation Training in Children With Unilateral Cerebral Palsy

TypeinterventionalSponsorKU LeuvenRan2014 to 2018Enrolled44ConditionsCerebral PalsyArmsConstraint-induced movement therapy, Action observation training, Placebo observation training
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Cristina Simon-MartinezKU Leuven, Department of Rehabilitation Sciences, Herestraat 49, bus 1510, Leuven, 3000, Belgium.ORCID https://orcid.org/0000-0001-6694-6358
Lisa MailleuxKU Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Jasmine HoskensKU Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Els OrtibusKU Leuven, Department of Development and Regeneration, Leuven, Belgium.
Ellen JaspersNeural Control of Movement Lab, Department of Health Sciences and Technology, ETH Zurich, Switzerland.
Nicole WenderothNeural Control of Movement Lab, Department of Health Sciences and Technology, ETH Zurich, Switzerland.
Giuseppina SgandurraDepartment of Developmental Neuroscience, IRCCS Fondazione Stella Maris, Calambrone, Italy.
Giovanni CioniDepartment of Developmental Neuroscience, IRCCS Fondazione Stella Maris, Calambrone, Italy.
Guy MolenaersKU Leuven, Department of Development and Regeneration, Leuven, Belgium.
Katrijn KlingelsKU Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Hilde FeysKU Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
KU Leuven · BEETH Zurich · CHUniversity of Pisa · ITHasselt University · BEHES-SO University of Applied Sciences and Arts Western Switzerland · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionConstraint-induced movement therapy (CIMT) improves upper limb (UL) motor execution in unilateral cerebral palsy (uCP). As these children also show motor planning deficits, action-observation training (AOT) might be of additional value. Here, we investigated the combined effect of AOT to CIMT and identified factors influencing treatment response.

methodsA total of 44 children with uCP (mean 9 years 6 months, SD 1 year 10 months) participated in a 9-day camp wearing a splint for 6 h/day and were allocated to the CIMT + AOT (

resultsAlthough no between-groups differences were found (

conclusionsAdding AOT to CIMT, resulted in a better outcome for children with poor motor function and high amounts of mirror movements. CIMT with or without AOT seems to be more beneficial for children with poor sensory function.

trial registrationRegistered at ClinicalTrials.gov on 22nd August 2017 (ClinicalTrials.gov identifier: NCT03256357).

Indexed as

Action Observation TrainingConstraint Induced Movement TherapyCorticospinal Tract Wiring PatternIntensive trainingPredictorsRandomized Controlled TrialsUnilateral cerebral palsyUpper limb

Identifiers

PMID32031542
PMCPMC6977217
OpenAlexW3000202296

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.