ArticleObesity (Silver Spring, Md.)2020
Maternal Adiposity is Associated with Fat Mass Accretion in Female but not Male Offspring During the First 2 Years of Life.
Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 19 citations in OpenAlex.
- Associations between maternal adiposity during pregnancy and neonatal brain cortical development.NeuroImage · 2026Article
- Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Tracing PFAS Transfer from Mother to the Fetoplacental Unit: Insights from Trimester-Specific Maternal Serum Profiles.bioRxiv : the preprint server for biology · 2026Article
- The Effect of a Supervised Exercise Program Throughout Pregnancy on Longitudinal Lipid Profile Changes: A Randomized Clinical Trial.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2026Article
- Maternal obesity alters adipogenic potential and mitochondrial maximal respiration in infant mesenchymal stem cells.Frontiers in endocrinology · 2026Article
- General obesity index or central obesity indicators: which is a better predictor of body fat percentage in the first trimester?BMC pregnancy and childbirth · 2025Article
- Individual and mixture associations of placental per- and polyfluoroalkyl substance with neurodevelopment at 12 and 24 months of age.Environmental advances · 2025Article
- Excessive Gestational Weight Gain, Independent of Body Mass Index, Is Associated With Child Fat Mass Index at Age 2 Years in the Growing life, Optimizing Wellness Study.Journal of the Academy of Nutrition and Dietetics · 2025Observational
- Placental PFAS concentrations are associated with perturbations of placental DNA methylation.Environmental pollution (Barking, Essex : 1987) · 2025Article
- Childhood cardiometabolic risk factors associated with the perinatal environment of the maternal-paternal-child triad.Pediatric obesity · 2024Article
- Placental PFAS concentrations are associated with perturbations of placental DNA methylation at loci with important roles on cardiometabolic health.medRxiv : the preprint server for health sciences · 2024Article
- Offspring sex modifies the association between early-pregnancy adiposity and 2-year-old physical activity-The Glowing Study.International journal of obesity (2005) · 2024Article
- Physical Activity, Sedentary and Sleep Phenotypes in Women During the First Trimester of Pregnancy.Maternal and child health journal · 2023Article
- Association between maternal and infant screen time with child growth and development: A longitudinal study.Pediatric obesity · 2023Article
- Type 2 Diabetes in Youth: the Role of Early Life Exposures.Current diabetes reports · 2020Review
- Body Composition Measurements from Birth through 5 Years: Challenges, Gaps, and Existing & Emerging Technologies-A National Institutes of Health workshop.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveThis study investigated which antenatal and postnatal factors determine offspring adiposity during the first 2 years of life.
methodsParticipants were mother and child pairs (N = 224). Offspring percent fat mass (%FM) was obtained using quantitative nuclear magnetic resonance at 11 time points between ages 0.5 and 24 months. Independent variables included race, age, gestational weight gain, first-trimester %FM, delivery mode, gestational measures of resting energy expenditure, respiratory exchange ratio, physical activity, serum cytokines and lipids, and dietary intake for the mothers, as well as sex, birth weight and length, breastfeeding duration, and physical activity at age 2 years for the children. Linear mixed models were used to construct the best-fitted models for the entire cohort and for each sex.
resultsMaternal %FM (P = 0.006), high-density lipoprotein (HDL) (P < 0.001), and breastfeeding duration (P = 0.023) were positively associated with female offspring adiposity, whereas maternal dietary fiber intake (P = 0.016) had a negative association. Birth weight (P = 0.004), maternal HDL (P = 0.013), and breastfeeding duration (P = 0.015) were all positively associated with male offspring adiposity.
conclusionsAntenatal and postnatal factors differentially impact male and female offspring adiposity during the first 2 years of life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.