Evidence map›Paper›PMID 32030913›Full record

ArticlePharmacology research & perspectives2020

Combination drug therapy against OAB normalizes micturition parameters and increases the release of nitric oxide during chemically induced cystitis.

Bhavik Patel, Fernando Perez, Patrik Aronsson, Ranya Alothmani, Thomas Carlsson, Michael Winder

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bhavik PatelDepartment of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK.ORCID 0000-0002-8773-3850
Fernando PerezDepartment of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK.
Patrik AronssonDepartment of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ranya AlothmaniDepartment of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Thomas CarlssonDepartment of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Michael WinderDepartment of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-2527-4713
University of Gothenburg · SEUniversity of Brighton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Today, monotherapy is the most common pharmacological treatment option for patients suffering from overactive bladder (OAB). Recent reports have indicated potential benefits of combination therapy, using a muscarinic antagonist and a β

Indexed as

AcetanilidesAnimalsCyclophosphamideCystitisDisease Models, AnimalDrug Therapy, CombinationMaleNitric OxideRandom AllocationRatsRats, Sprague-DawleyThiazolesTolterodine TartrateTreatment OutcomeUrinary Bladder, OveractiveAcetanilidesCyclophosphamidemirabegronNitric OxideThiazolesTolterodine Tartratecyclophosphamidecystitismicturition parametersmirabegronnitric oxidetolterodineurinary bladder

Identifiers

PMID32030913
PMCPMC7005531
OpenAlexW3004626953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.