Evidence map›Paper›PMID 32030911›Full record

Trial reportObesity (Silver Spring, Md.)2020

Increased Visceral Adipose Tissue Without Weight Retention at 59 Weeks Postpartum.

Isaiah Janumala, Tatiana Toro-Ramos, Elizabeth Widen, Barak Rosenn, Janet Crane, Michelle Horowitz, Susan Lin, Sonia Gidwani, Charles Paley, John C Thornton and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Impact of Maternal Body Composition, Hydration, and Metabolic Health on Breastfeeding Success: A Comprehensive Review.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Review
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Isaiah JanumalaNew York Obesity Research Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Tatiana Toro-RamosNew York Obesity Research Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Elizabeth WidenNew York Obesity Research Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.ORCID 0000-0002-9574-6109
Barak RosennDepartment of Obstetrics and Gynecology, Mount Sinai West Hospital, Mount Sinai Health System, Icahn School of Medicine, New York, New York, USA.
Janet CraneNew York Obesity Research Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Michelle HorowitzNew York Obesity Research Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Susan LinCenter for Family and Community Medicine, Columbia University, New York, New York, USA.
Sonia GidwaniDepartment of Pediatrics, Mount Sinai West Hospital, Mount Sinai Health System, Icahn School of Medicine, New York, New York, USA.
Charles PaleyDepartment of Pediatrics, Mount Sinai West Hospital, Mount Sinai Health System, Icahn School of Medicine, New York, New York, USA.
John C ThorntonThornton Consulting, Mahopac, New York, USA.
F Xavier Pi-SunyerNew York Obesity Research Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Dympna GallagherNew York Obesity Research Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.ORCID 0000-0003-1769-9754

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Predictors of Recidivism to Obesity in Weight-Reduced IndividualsUH3DK128302 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DYMPNA GALLAGHER, RUDOLPH L LEIBEL · 2022 to 2026
$7.0M
Weight Management in Obese Pregnant Underserved African American WomenU01DK094416 · NIDDK · WASHINGTON UNIVERSITY · PI CAHILL, ALISON G, HAIRE-JOSHU, DEBRA · 2011 to 2017
$5.3M
Lifestyle Interventions in Overweight and Obese Pregnant WomenU01DK094463 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI GALLAGHER, DYMPNA, PI-SUNYER, XAVIER · 2011 to 2017
$5.3M
Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI MARK D. HAYWARD · 2017 to 2026
$5.2M
Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT)U01HL114344 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PEACEMAN, ALAN M, VAN HORN, LINDA VERNER · 2011 to 2017
$4.9M
Preventing excessive gestational weight gain in obese womenU01HL114377 · NHLBI · CALIFORNIA POLY STATE U SAN LUIS OBISPO · PI PHELAN, SUZANNE · 2011 to 2016
$4.5M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
RCU for Lifestyle Interventions in Overweight and Obese Pregnant Women ConsortiumU01DK094466 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI CLIFTON, REBECCA GERSNOVIEZ, DREWS, KIMBERLY LEE · 2011 to 2016
$4.1M
Pregnancy and EARly Lifestyle improvement Study (PEARLS)U01HD072834 · NICHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI FRANKS, PAUL WILLIAM, JOSHIPURA, KAUMUDI J · 2011 to 2016
$3.7M
Promoting fat loss during pregnancy in women with grade 2 and 3 obesityR01DK124806 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI PHELAN, SUZANNE, REDMAN, LEANNE MAREE · 2020 to 2024
$3.2M
Prevention of postparutm weight retention in low income WIC womenR01DK087889 · NIDDK · CALIFORNIA POLY STATE U SAN LUIS OBISPO · PI PHELAN, SUZANNE · 2011 to 2015
$3.0M
National Center for Complementary and Alternative Medicine U01-DK094463National Institute of Child Health and Human Development K99/R00HD086304NHLBI NIH HHS U01 HL114344NHLBI NIH HHS U01 HL114344, U01 HL114377NHLBI NIH HHS U01 HL114377NHLBI NIH HHS UG3 HL163508NHLBI NIH HHS UH3 HL163508NICHD NIH HHS K99 HD086304NICHD NIH HHS P2C HD042849NICHD NIH HHS R00 HD086304NICHD NIH HHS R01 HD084282NICHD NIH HHS U01 HD072834NIDDK NIH HHS P30 DK026687NIDDK NIH HHS P30-DK026687NIDDK NIH HHS R01 DK071667NIDDK NIH HHS R01 DK087889NIDDK NIH HHS R01 DK108661NIDDK NIH HHS R01 DK124806NIDDK NIH HHS R56 DK108661NIDDK NIH HHS T32 DK007559NIDDK NIH HHS T32-DK007559NIDDK NIH HHS T32 DK091227NIDDK NIH HHS T32-DK091227NIDDK NIH HHS U01 DK094416NIDDK NIH HHS U01 DK094418NIDDK NIH HHS U01 DK094463NIDDK NIH HHS U01 DK094466NIDDK NIH HHS U01DK094466NIDDK NIH HHS UH3 DK128302NIH Office of the Director U01-DK094463Office of Behavioral and Social Sciences Research U01-DK094463Office of Disease Prevention U01-DK094463Office of Research on Women's Health U01-DK094463
6 · The paper itself

Abstract

objectiveThis study aimed to determine whether controlling maternal gestational weight gain (GWG) influences adipose tissue distribution at 1 year postpartum.

methodsWomen with overweight or obesity (n = 210, BMI ≥ 25 or ≥ 30) were randomized to a lifestyle intervention (LI) designed to control GWG or to usual obstetrical care (UC). Measures included anthropometry, whole-body magnetic resonance imaging for visceral (VAT), intermuscular, and subcutaneous adipose tissue, and cardiometabolic risk factors in pregnancy (15 and 35 weeks) and after delivery (15 and 59 weeks).

resultsBaseline (15 weeks) characteristics were similar (mean [SD]: age, 33.8 [4.3] years; weight, 81.9 [13.7] kg; BMI, 30.4 [4.5]; gestational age at randomization, 14.9 [0.8] weeks). LI had less GWG (1.79 kg; P = 0.003) and subcutaneous adipose tissue gain at 35 weeks gestation (P < 0.01). UC postpartum weight (2.92 kg) was higher at 15 weeks but not different from baseline or LI at 59 weeks postpartum. Postpartum VAT increased from baseline in LI by 0.23 kg at 15 weeks and 0.55 kg at 59 weeks; in UC, it increased by 0.34 kg at 15 and 59 weeks. Intermuscular adipose tissue remained elevated in LI (0.22 kg) at 59 weeks. VAT was associated with several cardiometabolic risk factors at 59 weeks.

conclusionsDespite no weight retention at 59 weeks postpartum, women had increased VAT by ~30%. Postpartum modifiable behaviors are warranted to lower the risk of VAT retention.

Indexed as

AdultFemaleHumansIntra-Abdominal FatPostpartum PeriodPregnancyWhole Body Imaging

Identifiers

PMID32030911
PMCPMC7042094

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.