ArticleAngewandte Chemie (International ed. in English)2020
Amide Synthesis by Nickel/Photoredox-Catalyzed Direct Carbamoylation of (Hetero)Aryl Bromides.
Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Direct Mechano-Catalytic Synthesis of Amides Using Brass Balls via Cross-Coupling of Isocyanides With Arylboronic Acids or in Situ Generated N-Aryl-Pyridinium Salts.Chemistry, an Asian journal · 2026Article
- Cobaloxime-catalysed regiodivergent hydrogen atom transfer for alkenyl and allylic carbamoylation with branched alkenes.Nature communications · 2026Article
- Organocatalytic Synthesis of Amides Using Thioacids and Anilines via Electron Donor-Acceptor Photoactivation.The Journal of organic chemistry · 2026Article
- Activation of Cyanate Anions by Phosphine Radical Cations Enables Formal Hydrocarbamoylation of Alkenes.Angewandte Chemie (International ed. in English) · 2026Article
- Modular assembly of chiral amino acid derivatives and peptides from commonly available feedstocks.Nature communications · 2025Article
- Dual Catalytic Enantioconvergent Carbamoylation of Aziridines.Journal of the American Chemical Society · 2025Article
- Nickel-photoredox catalysis: merging photons with metal catalysts for organic synthesis.RSC advances · 2025Review
- Iron-Catalyzed Carbonylation Reactions with Carbon Monoxide.Angewandte Chemie (International ed. in English) · 2025Review
- Rapid Methylation of Aryl Bromides Using Air-Stable DABCO-Bis(Trimethylaluminum) via Nickel Metallaphotoredox Catalysis.Angewandte Chemie (International ed. in English) · 2025Article
- Innovative On-Resin and in Solution Peptidomimetics Synthesis via Metal-Free Photocatalytic Approach.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Article
- Versatile, Modular, and General Strategy for the Synthesis of α-Amino Carbonyls.Journal of the American Chemical Society · 2024Article
- Acyl-1,4-Dihydropyridines: Universal Acylation Reagents for Organic Synthesis.Molecules (Basel, Switzerland) · 2024Review
- Harnessing the potential of acyl triazoles in bifunctional cobalt-catalyzed radical cross-coupling reactions.Nature communications · 2024Article
- Visible light mediated iron-catalyzed addition of oxamic acids to imines.RSC advances · 2024Article
- Decarboxylative Nickel- and Photoredox-Catalyzed Aminocarbonylation of (Hetero)Aryl Bromides.Organic letters · 2024Article
- Redox-Neutral Decarboxylative Cross-Coupling of Oxamates with Aryl Bromides.ACS organic & inorganic Au · 2024Article
- Copper-catalyzed carbonylative multi-component borylamidation of alkenes for synthesizing γ-boryl amides with CO as both methylene and carbonyl sources.Chemical science · 2024Article
- A π-conjugated covalent organic framework enables interlocked nickel/photoredox catalysis for light-harvesting cross-coupling reactions.Chemical science · 2023Article
- Mechanochemical Defluorinative Arylation of Trifluoroacetamides: An Entry to Aromatic Amides.The Journal of organic chemistry · 2023Article
- The Merger of Benzophenone HAT Photocatalysis and Silyl Radical-Induced XAT Enables Both Nickel-Catalyzed Cross-Electrophile Coupling and 1,2-Dicarbofunctionalization of Olefins.ACS catalysis · 2022Article
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7 authors.
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Abstract
Herein, we report a one-electron strategy for catalytic amide synthesis that enables the direct carbamoylation of (hetero)aryl bromides. This radical cross-coupling approach, which is based on the combination of nickel and photoredox catalysis, proceeds at ambient temperature and uses readily available dihydropyridines as precursors of carbamoyl radicals. The method's mild reaction conditions make it tolerant of sensitive-functional-group-containing substrates and allow the installation of an amide scaffold within biologically relevant heterocycles. In addition, we installed amide functionalities bearing electron-poor and sterically hindered amine moieties, which would be difficult to prepare with classical dehydrative condensation methods.
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