Evidence map›Paper›PMID 32030519›Full record

ArticleEJNMMI physics2020

Explicit measurement of multi-tracer arterial input function for PET imaging using blood sampling spectroscopy.

Carlos Velasco, Adriana Mota-Cobián, Jesús Mateo, Samuel España

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Multiplexed imaging of radionuclides.Nature biomedical engineering · 2025
    Review
  2. Article
  3. Short 2-[Frontiers in medicine · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carlos VelascoCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Adriana Mota-CobiánCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Jesús MateoCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Samuel EspañaCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. sespana@ucm.es.ORCID http://orcid.org/0000-0001-9092-4597
Universidad Complutense de Madrid · ESSpanish National Centre for Cardiovascular Research · ES

Funding

Comunidad de Madrid 2016-T1/TIC-1099Instituto de Salud Carlos III FIS-FEDER PI14-01427Ministerio de Ciencia, Innovación y Universidades SEV-2015-0505Ministerio de Educación (ES) FPU014/01794
6 · The paper itself

Abstract

backgroundConventional PET imaging has usually been limited to a single tracer per scan. We propose a new technique for multi-tracer PET imaging that uses dynamic imaging and multi-tracer compartment modeling including an explicitly derived arterial input function (AIF) for each tracer using blood sampling spectroscopy. For that purpose, at least one of the co-injected tracers must be based on a non-pure positron emitter.

methodsThe proposed technique was validated in vivo by performing cardiac PET/CT studies on three healthy pigs injected with

resultsA high correlation was obtained between multi-tracer PET results, and those obtained from ex vivo analysis (

conclusionsThe proposed technique allows performing PET scans with two tracers during the same acquisition obtaining separate information for each tracer.

Indexed as

Arterial input functionGamma spectroscopyMulti-tracer PETPositron emission tomography

Identifiers

PMID32030519
PMCPMC7005194
OpenAlexW3012844923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.