Evidence map›Paper›PMID 32030360›Full record

ArticleCurrent opinion in toxicology2019

Systems Modeling of Developmental Vascular Toxicity.

Katerine S Saili, Jill A Franzosa, Nancy C Baker, Robert G Ellis-Hutchings, Raja S Settivari, Edward W Carney, Richard Spencer, Todd J Zurlinden, Nicole C Kleinstreuer, Shuaizhang Li and 2 more

Open access · greenAbstract read
In one paragraph

Article in Current opinion in toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Use of computational toxicology tools to predictCurrent research in toxicology · 2022
    Article
  4. Article
  5. Computational Biology andCurrent opinion in toxicology · 2020
    Article
  6. Application of In Vitro Metabolism Activation in High-Throughput Screening.International journal of molecular sciences · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Human Cell-BasedFrontiers in big data · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Katerine S SailiNational Center for Computational Toxicology (NCCT), Office of Research and Development (ORD), U.S. Environmental Protection Agency (USEPA) Research Triangle Park NC 27711.
Jill A FranzosaNational Center for Computational Toxicology (NCCT), Office of Research and Development (ORD), U.S. Environmental Protection Agency (USEPA) Research Triangle Park NC 27711.
Nancy C BakerNational Center for Computational Toxicology (NCCT), Office of Research and Development (ORD), U.S. Environmental Protection Agency (USEPA) Research Triangle Park NC 27711.
Robert G Ellis-HutchingsToxicology and Environmental Research and Consulting The Dow Chemical Company, Midland, MI 48674.
Raja S SettivariToxicology and Environmental Research and Consulting The Dow Chemical Company, Midland, MI 48674.
Edward W CarneyToxicology and Environmental Research and Consulting The Dow Chemical Company, Midland, MI 48674.
Richard SpencerARA, Research Triangle Park NC 27711.
Todd J ZurlindenNational Center for Computational Toxicology (NCCT), Office of Research and Development (ORD), U.S. Environmental Protection Agency (USEPA) Research Triangle Park NC 27711.
Nicole C KleinstreuerNational Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS) Research Triangle Park, NC 27711.
Shuaizhang LiNational Center for Advancing Translational Sciences (NCATS) National Institutes of Health, Bethesda, MD 20892.
Menghang XiaNational Center for Advancing Translational Sciences (NCATS) National Institutes of Health, Bethesda, MD 20892.
Thomas B KnudsenNational Center for Computational Toxicology (NCCT), Office of Research and Development (ORD), U.S. Environmental Protection Agency (USEPA) Research Triangle Park NC 27711.ORCID 0000-0002-5036-596x
Environmental Protection Agency · USDow Chemical (India) · INNational Institutes of Health · USLeidos (United States) · USNational Institute of Environmental Health Sciences · USResearch Triangle Park Foundation · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

The more than 80,000 chemicals in commerce present a challenge for hazard assessments that toxicity testing in the 21

Indexed as

5HPP-33Adverse outcome pathwayangiogenesisTNP-470Tox21ToxCast

Identifiers

PMID32030360
PMCPMC7004230
OpenAlexW2944481922

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.