Evidence map›Paper›PMID 32030257›Full record

ArticleJournal of thoracic disease2019

Preoperative hypoxemia in patients with type A acute aortic dissection: a retrospective study on incidence, related factors and clinical significance.

Zijian Guo, Yanwei Yang, Mingming Zhao, Bo Zhang, Jiakai Lu, Mu Jin, Weiping Cheng

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05874700 (A Pilot Study of Perioperative Application of Sivelestat Sodium in Acute Type A Aortic Dissection Patients With Preoperative Moderate to Severe Hypoxemia to Shorten the Duration of Postoperative Invasive Mechanical Ventilation), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05874700 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Pilot Study of Perioperative Application of Sivelestat Sodium in Acute Type A Aortic Dissection Patients With Preoperative Moderate to Severe Hypoxemia to Shorten the Duration of Postoperative Invasive Mechanical Ventilation

TypeinterventionalSponsorXiaotong HouRan2023 to 2024Enrolled30ConditionsAcute Aortic DissectionArmsSivelestat sodium was given intravenously, Placebo was given intravenously
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Zijian GuoDepartment of Anesthesiology, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
Yanwei YangDepartment of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Mingming ZhaoDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.
Bo ZhangDepartment of Mathematics, University of Essex, Colchester, UK.
Jiakai LuDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.
Mu JinDepartment of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Weiping ChengDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, China.
Capital Medical University · CNBeijing Friendship Hospital · CNPeking University · CNUniversity of Essex · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPre-operative hypoxemia (HO) is a serious complication occurring in acute type A aortic dissection (AAD) patients.

methodsThis was a retrospective study of 505 patients who underwent Stanford type A acute aortic dissection surgery in Anzhen hospital, Beijing, China, between January 2015 to February 2018. Patients were divided into a HO(+) group (PaO

resultsPreoperative HO occurred in 46.5% (235/505) of patients. Mean patient age was 47.8±9.6 years, and 189 (80.4%) were male. Multivariable logistic regression analysis showed a correlation between preoperative serum level of fibrinogen [95% confidence interval (CI), 0.95-0.99], white blood cell count (WBC) (95% CI, 1.07-1.18), systolic blood pressure (95% CI, 0.98-1.00), history of smoking (95% CI, 1.05-2.11) and pleural effusion (95% CI, 1.14-2.71) with preoperative HO. The HO(+) group had a significantly higher mortality than the HO(-) group (8.1%

conclusionsAAD patients were easy to have pre-operative HO, which had a higher morbidity than those without HO. Altered fibrinogen, WBC, systolic blood pressure levels, positive smoking history, and pleural effusion were associated with the presence of HO. More monitoring and treatment should be given to these patients.

Indexed as

Acute type A aortic dissection (acute AAD)hypoxemiarelated factors

Identifiers

PMID32030257
PMCPMC6988070
OpenAlexW2996057098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.