Evidence map›Paper›PMID 32030216›Full record

ArticleJournal of thoracic disease2019

Associations between changes in oxygenation, dead space and driving pressure induced by the first prone position session and mortality in patients with acute respiratory distress syndrome.

David M van Meenen, Jan-Paul Roozeman, Ary Serpa Neto, Paolo Pelosi, Marcelo Gama de Abreu, Janneke Horn, Olaf L Cremer, Frederique Paulus, Marcus J Schultz, MARS Consortium

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Changes in Driving Pressure vs Oxygenation as Predictor of Mortality in Moderate to Severe Acute Respiratory Distress Syndrome Patients Receiving Prone Position Ventilation.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Observational
  11. Review
  12. Article
  13. Article
  14. Respiratory Support in COVID-19 Patients, with a Focus on Resource-Limited Settings.The American journal of tropical medicine and hygiene · 2020
    Review
  15. Review
  16. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 6 countries.

David M van MeenenDepartment of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Jan-Paul RoozemanDepartment of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Ary Serpa NetoDepartment of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Paolo PelosiDepartment of Surgical Sciences and Integrated Diagnostics, IRCCS AOU San Martino IST, University of Genoa, Genoa, Italy.
Marcelo Gama de AbreuPulmonary Engineering Group, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Janneke HornDepartment of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Olaf L CremerDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Frederique PaulusDepartment of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Marcus J SchultzDepartment of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
MARS Consortium
Amsterdam University Medical Centers · NLHospital Israelita Albert Einstein · BRMahidol Oxford Tropical Medicine Research Unit · THUniversity Hospital Carl Gustav Carus · DEUniversity Medical Center Utrecht · NLUniversity of Amsterdam · NLUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutcome prediction in acute respiratory distress syndrome (ARDS) is challenging, especially in patients with severe hypoxemia. The aim of the current study was to determine the prognostic capacity of changes in PaO

methodsThis was a post hoc analysis of the conveniently-sized 'Molecular Diagnosis and Risk Stratification of Sepsis' study (MARS). The current analysis included ARDS patients who were placed in the PP. The primary endpoint was the prognostic capacity of the PP-induced changes in PaO

resultsNinety patients were included; 28-day mortality was 46%. PP-induced changes in PaO

conclusionsChanges in PaO

Indexed as

Acute respiratory distress syndrome (ARDS)dead spacedriving pressuremortalityoxygenationPaO2/FiO2prognosticationprone position (PP)refractory hypoxemiarespiratory system driving pressureVD/VTΔPΔPRS

Identifiers

PMID32030216
PMCPMC6987992
OpenAlexW2997058154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.