ArticleJournal of tissue engineering
Clinical study of octacalcium phosphate and collagen composite in oral and maxillofacial surgery.
Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 70 citations in OpenAlex.
- Effect of combination of osteoblasts and octacalcium phosphate collagen composite on bone regeneration in rat calvarial bone defect.Medical molecular morphology · 2026Article
- Alveolar Bone Augmentation Using Octacalcium Phosphate and Collagen Composite with Custom-Made Titanium Mesh: A Case Report.The American journal of case reports · 2025Article
- Recent Advances in Octacalcium Phosphate with Incorporated Carboxylate Ions: A Review.Molecules (Basel, Switzerland) · 2025Review
- Octacalcium Phosphate/Calcium Citrate/Methacrylated Gelatin Composites: Optimization of Photo-Crosslinking Conditions and Osteogenic Potential Evaluation.International journal of molecular sciences · 2025Article
- Effect of Octacalcium Phosphate on Osteogenic Differentiation of Induced Pluripotent Stem Cells in a 3D Hybrid Spheroid Culture.Biomimetics (Basel, Switzerland) · 2025Article
- Enhanced osteogenic capacity of octacalcium phosphate involving adsorption of stromal-derived factor-1 in a standardized defect of a rat femur.Journal of materials science. Materials in medicine · 2025Article
- Adsorption of Serum Fetuin onto Octacalcium Phosphate and Its Relation to Osteogenic Property.International journal of molecular sciences · 2025Article
- Advances in Bioceramics for Bone Regeneration: A Narrative Review.Biomimetics (Basel, Switzerland) · 2024Review
- Ridge preservation using octacalcium phosphate collagen to induce new bone containing a vascular network of mainly Type H vessels.Scientific reports · 2024Article
- An Up-to-Date Review of Materials Science Advances in Bone Grafting for Oral and Maxillofacial Pathology.Materials (Basel, Switzerland) · 2024Review
- From Tooth Adhesion to Bioadhesion: Development of Bioabsorbable Putty-like Artificial Bone with Adhesive to Bone Based on the New Material "Phosphorylated Pullulan".Materials (Basel, Switzerland) · 2024Review
- Volume change after maxillary sinus floor elevation with apatite carbonate and octacalcium phosphate.International journal of implant dentistry · 2024Article
- Calcium Phosphate Biomaterials for 3D Bioprinting in Bone Tissue Engineering.Biomimetics (Basel, Switzerland) · 2024Review
- Potentials of pure xenograft materials in maxillary ridge augmentation: A case series.The Saudi dental journal · 2024Article
- Synthesis of Octacalcium Phosphate Containing Glutarate Ions with a High Incorporation Fraction.Materials (Basel, Switzerland) · 2022Article
- Acceleration of bone formation by octacalcium phosphate composite in a rat tibia critical-sized defect.Journal of orthopaedic translation · 2022Article
- Correction of large jawbone defect in the mouse using immature osteoblast-like cells and a 3D polylactic acid scaffold.PNAS nexus · 2022Article
- Bone Tissue Engineering in Rat Calvarial Defects Using Induced Bone-like Tissue by rhBMPs from Immature Muscular Tissues In Vitro.International journal of molecular sciences · 2022Article
- Preparation of antimicrobial calcium phosphate/protamine composite powders with fluoride ions using octacalcium phosphate.Journal of materials science. Materials in medicine · 2022Article
- Utility of Chitra-HASi Granules in Cystic Defects of the Maxillofacial Region: A Pilot Study.Journal of pharmacy & bioallied sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Octacalcium phosphate and its collagen composite have been recognized as bone substitute materials possessing osteoconductivity and biodegradation properties. We evaluated the effectiveness of octacalcium phosphate and its collagen composite used for bone augmentation in major oral and maxillofacial surgeries in a clinical trial. Octacalcium phosphate and its collagen composite were used in cases of sinus floor elevation in 1- and 2-stage, socket preservation, cyst, and alveolar cleft procedures. A total of 60 patients were evaluated for effectiveness after the implantation of octacalcium phosphate and its collagen composite. Although sinus floor elevation in 1-stage, cyst, and alveolar cleft cases met the criteria for the judgment of success, sinus floor elevation in 2-stage and socket preservation groups did not meet the criteria in the initial evaluation. However, an additional evaluation for reconfirmation revealed the effectiveness of octacalcium phosphate and its collagen composite in those groups, and all evaluation results ultimately indicated the success of this clinical trial. Therefore, this clinical trial suggested that application of octacalcium phosphate and its collagen composite for oral and maxillofacial surgery was safe and effective and that octacalcium phosphate and its collagen composite could be a bone substitute candidate instead of autologous bone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.