ArticleNature communications2020
Community diversity and habitat structure shape the repertoire of extracellular proteins in bacteria.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 40 citations in OpenAlex.
- From predicted bacteriocins to ecological function.Current research in microbial sciences · 2026Review
- Low Levels of Amino Acid Auxotrophy Among Environmental Pseudomonas Isolates.Environmental microbiology · 2026Article
- The Evolutionary and Ecological Consequences of Cooperation.The American naturalist · 2026Review
- Cooperation and the evolution of bacterial niche breadth.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Spatial structure: shaping the ecology and evolution of microbial communities.FEMS microbiology reviews · 2026Review
- A phylogenetic approach to comparative genomics.Nature reviews. Genetics · 2025Review
- Impact of vancomycin and Clostridioides difficile on the secretome and pathogenicity of Clostridium innocuum.Medical microbiology and immunology · 2025Article
- Ayu: a machine intelligence tool for identification of extracellular proteins in the marine secretome.Nature communications · 2025Article
- Shotgun metagenomics reveals antibiotic resistome dynamics and metabolic specialization in fungal-dominated microbiomes.Frontiers in microbiology · 2025Article
- Parallel ecological and evolutionary responses to selection in a natural bacterial community.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genes for cooperation are not more likely to be carried by plasmids.Proceedings. Biological sciences · 2024Article
- Revisiting the Multifaceted Roles of Bacteriocins : The Multifaceted Roles of Bacteriocins.Microbial ecology · 2024Review
- Ecological dependencies and the illusion of cooperation in microbial communities.Microbiology (Reading, England) · 2024Article
- Niche breadth specialization impacts ecological and evolutionary adaptation following environmental change.The ISME journal · 2024Article
- GDPF: a data resource for the distribution of prokaryotic protein families across the global biosphere.Nucleic acids research · 2024Article
- SOCfinder: a genomic tool for identifying social genes in bacteria.Microbial genomics · 2023Article
- Signatures of kin selection in a natural population of the bacteriaEvolution letters · 2023Article
- Siderophore-mediated iron partition promotes dynamical coexistence between cooperators and cheaters.iScience · 2023Article
- A social niche breadth score reveals niche range strategies of generalists and specialists.Nature ecology & evolution · 2023Article
- Genomic analysis ofFrontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We test the hypothesis that the frequency and cost of extracellular proteins produced by bacteria, which often depend on cooperative processes, vary with habitat structure and community diversity. The integration of the environmental distribution of bacteria (using 16S datasets) and their genomes shows that bacteria living in more structured habitats encode more extracellular proteins. In contrast, the effect of community diversity depends on protein function: it's positive for proteins implicated in antagonistic interactions and negative for those involved in nutrient acquisition. Extracellular proteins are costly and endure stronger selective pressure for low cost and for low diffusivity in less structured habitats and in more diverse communities. Finally, Bacteria found in multiple types of habitats, including host-associated generalists, encode more extracellular proteins than niche-restricted bacteria. These results show that ecological variables, notably habitat structure and community diversity, shape the evolution of the repertoires of genes encoding extracellular proteins and thus affect the ability of bacteria to manipulate their environment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.