ArticleNature communications2020
Weak functional group interactions revealed through metal-free active template rotaxane synthesis.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The trial behind it
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Who cites it
25 citing papers in PubMed, 78 citations in OpenAlex.
- Inverted metal-free active template synthesis of rotaxanes via axle‑mediated macrocyclization.Nature chemistry · 2026Article
- Metal-Free Active Template: A Straightforward Route to 4-Aminopyridinium-Based Rotaxane Molecular Shuttles.Angewandte Chemie (International ed. in English) · 2026Article
- Manipulating excited-state dynamics through macrocycle positioning in a rotaxane for sensitive and discriminative methanol sensing.Chemical science · 2026Article
- Spatial Assembly of Mechanically Planar Chiral Rotaxanes on Rationally Designed Cavitands.Angewandte Chemie (International ed. in English) · 2025Article
- Control of Tetrazine Bioorthogonal Reactivity by Rotaxanation.Angewandte Chemie (International ed. in English) · 2025Article
- Programmable molecular dethreading towards tunable drug release.Nature communications · 2025Article
- Crown Ether-Peptide Rotaxanes.Angewandte Chemie (International ed. in English) · 2025Article
- Spotlight on Mechanosterics: A Bulky Macrocycle Promotes Functional Group Reactivity in a [2]Rotaxane.Journal of the American Chemical Society · 2025Article
- Autonomous Dynamic Control of Crown Ether Cargo Release from [2]Rotaxane Carriers in a Piperidine Oscillator.Journal of the American Chemical Society · 2025Article
- A Thiourea-Based Rotaxane Catalyst: Nucleophilic Fluorination Phase-Transfer Process Unlocked by the Mechanical Bond.Organic letters · 2025Article
- Skeletal Editing of Mechanically Interlocked Molecules: Nitrogen Atom Deletion from Crown Ether-Dibenzylammonium Rotaxanes.Journal of the American Chemical Society · 2024Article
- BuildAMol: a versatile Python toolkit for fragment-based molecular design.Journal of cheminformatics · 2024Article
- The effect of host size on binding in host-guest complexes of cyclodextrins and polyoxometalates.Chemical science · 2024Article
- Molecular entanglement can strongly increase basicity.Communications chemistry · 2024Review
- Compact Rotaxane Superbases.Journal of the American Chemical Society · 2023Article
- Transamidation-Driven Molecular Pumps.Journal of the American Chemical Society · 2022Article
- Unsprung traps keep PARP inhibitors effective.Nature cell biology · 2022Article
- a-PET and Weakened Triplet-Triplet Annihilation Self-Quenching Effects in Benzo-21-Crown-7-Functionalized Diiodo-BODIPY.ACS omega · 2021Article
- Self-Assembly of Stimuli-Responsive [2]Rotaxanes by Amidinium Exchange.Journal of the American Chemical Society · 2021Article
- A catalysis-driven artificial molecular pump.Nature · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modest functional group interactions can play important roles in molecular recognition, catalysis and self-assembly. However, weakly associated binding motifs are often difficult to characterize. Here, we report on the metal-free active template synthesis of [2]rotaxanes in one step, up to 95% yield and >100:1 rotaxane:axle selectivity, from primary amines, crown ethers and a range of C=O, C=S, S(=O)
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.