Evidence map›Paper›PMID 32029596›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Loss of phenotypic inheritance associated with

Suzanne M Hingley-Wilson, Nan Ma, Yin Hu, Rosalyn Casey, Anders Bramming, Richard J Curry, Hongying Lilian Tang, Huihai Wu, Rachel E Butler, William R Jacobs and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Infection and drug resistance · 2023
    Article
  8. Review
  9. Isolation of Persister Cells ofInternational journal of molecular sciences · 2021
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Suzanne M Hingley-WilsonDepartment of Microbial and Cellular Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom.ORCID 0000-0002-6514-1424
Nan MaDepartment of Microbial and Cellular Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom.
Yin HuDepartment of Computer Science, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom.
Rosalyn CaseyDepartment of Microbial and Cellular Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom.
Anders BrammingDepartment of Forensic Medicine, University of Southern Denmark, DK-5320 Ribe, Denmark.
Richard J CurryPhoton Science Institute, Department of Electrical and Electronic Engineering, The University of Manchester, Manchester M13 9PL, United Kingdom.ORCID 0000-0001-8859-5210
Hongying Lilian TangDepartment of Computer Science, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom.
Huihai WuDepartment of Microbial and Cellular Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom.
Rachel E ButlerDepartment of Microbial and Cellular Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom.
William R JacobsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461; j.mcfadden@surrey.ac.uk william.jacobs@einsteinmed.org a.rocco@surrey.ac.uk.ORCID 0000-0003-3321-3080
Andrea RoccoDepartment of Microbial and Cellular Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom; j.mcfadden@surrey.ac.uk william.jacobs@einsteinmed.org a.rocco@surrey.ac.uk.ORCID 0000-0002-0974-5522
Johnjoe McFaddenDepartment of Microbial and Cellular Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom; j.mcfadden@surrey.ac.uk william.jacobs@einsteinmed.org a.rocco@surrey.ac.uk.ORCID 0000-0003-2145-0046
University of Surrey · GBAlbert Einstein College of Medicine · USUniversity of Manchester · GBUniversity of Southern Denmark · DK

Funding

Molecular Genetic Analysis of Mycobacterium TuberculosisR37AI026170 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI WILLIAM Robert JACOBS · 2004 to 2026
$7.7M
MOLECULAR GENETIC ANALYSIS OF MYCOBACTERIUM TUBERCULOSISR01AI026170 · NIAID · YESHIVA UNIVERSITY · PI JACOBS, WILLIAM ROBERT · 1989 to 2022
$7.1M
Biotechnology and Biological Sciences Research Council BB/J002097/1Biotechnology and Biological Sciences Research Council BB/J004243/1Medical Research Council MR/K001744/1Medical Research Council MR/N007328/1NIAID NIH HHS R01 AI026170NIAID NIH HHS R37 AI026170
6 · The paper itself

Abstract

Whenever a genetically homogenous population of bacterial cells is exposed to antibiotics, a tiny fraction of cells survives the treatment, the phenomenon known as bacterial persistence [G.L. Hobby

Indexed as

AmpicillinAnti-Bacterial AgentsDNA-Binding ProteinsDrug Resistance, BacterialEscherichia coliEscherichia coli ProteinsMicrofluidicsModels, BiologicalMutationTranscription FactorsAmpicillinAnti-Bacterial AgentsDNA-Binding ProteinsEscherichia coli ProteinsTranscription FactorsydcI protein, E coliantibiotic resistancemicrobiologypersistencephenotypicsystems biology

Identifiers

PMID32029596
PMCPMC7049120
OpenAlexW3004514707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.