Evidence map›Paper›PMID 32029475›Full record

ArticleThe Journal of biological chemistry2020

Allosteric regulation of menaquinone (vitamin K

Ghader Bashiri, Laura V Nigon, Ehab N M Jirgis, Ngoc Anh Thu Ho, Tamsyn Stanborough, Stephanie S Dawes, Edward N Baker, Esther M M Bulloch, Jodie M Johnston

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Menaquinone biosynthesis inEngineering microbiology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Structures of Listeria monocytogenes MenD in ThDP-bound and in-crystallo captured intermediate I-bound forms.Acta crystallographica. Section F, Structural biology communications · 2025
    Article
  7. Review
  8. Increasing Vitamin KJournal of agricultural and food chemistry · 2024
    Article
  9. Article
  10. Allosteric inhibition ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  11. Article
  12. Biosynthesis of Menaquinone in E. coli: Identification of an Elusive Isomer of SEPHCHC.Chembiochem : a European journal of chemical biology · 2022
    Article
  13. Review
  14. Review
  15. Review
  16. Self-control of vitamin KThe Journal of biological chemistry · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ghader BashiriLaboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand.ORCID 0000-0002-5092-3749
Laura V NigonLaboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand.ORCID 0000-0003-0577-2918
Ehab N M JirgisLaboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand.
Ngoc Anh Thu HoSchool of Physical and Chemical Sciences, Biomolecular Interaction Centre (BIC), and Maurice Wilkins Centre for Molecular Biodiscovery, University of Canterbury, Christchurch 8041, New Zealand.ORCID 0000-0001-9291-8860
Tamsyn StanboroughSchool of Physical and Chemical Sciences, Biomolecular Interaction Centre (BIC), and Maurice Wilkins Centre for Molecular Biodiscovery, University of Canterbury, Christchurch 8041, New Zealand.ORCID 0000-0001-5945-2536
Stephanie S DawesLaboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand.
Edward N BakerLaboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand.ORCID 0000-0003-2456-7661
Esther M M BullochLaboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand.ORCID 0000-0002-4262-1791
Jodie M JohnstonSchool of Physical and Chemical Sciences, Biomolecular Interaction Centre (BIC), and Maurice Wilkins Centre for Molecular Biodiscovery, University of Canterbury, Christchurch 8041, New Zealand jodie.johnston@canterbury.ac.nz.ORCID 0000-0003-4895-0243
University of Auckland · NZUniversity of Canterbury · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Menaquinone (vitamin K

Indexed as

Allosteric RegulationAllosteric SiteAmino Acid SequenceBacterial ProteinsBinding SitesBiocatalysisCatalytic DomainCrystallography, X-RayHumansMutagenesis, Site-DirectedMycobacterium tuberculosisNaphtholsProtein ConformationRecombinant ProteinsSequence AlignmentVitamin K 21,4-dihydroxy-2-naphthoic acidBacterial ProteinsNaphtholsRecombinant ProteinsVitamin K 2allosteric regulationallosterycooperativityfeedback inhibition, 1,4-dihydroxy-2-naphthoic acid (DHNA)menaquinone (vitamin K2) biosynthesis, drug targetMycobacterium tuberculosispyruvate oxidase (POX) enzymesSEPHCHC synthase (MenD)structural biologythiamine diphosphate (ThDP)-dependent enzymesvitamin K

Identifiers

PMID32029475
PMCPMC7086027
OpenAlexW3004886518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.