ArticleAJNR. American journal of neuroradiology2020
Endovascular Thrombectomy of Calcified Emboli in Acute Ischemic Stroke: A Multicenter Study.
Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Mechanical Thrombectomy in the Management of Acute Ischemic Stroke Secondary to Calcified Cerebral Emboli: a Systematic Review.Clinical neuroradiology · 2026Pooled it
- Peri-procedural recognition of a calcified cerebral embolus following mechanical thrombectomy: A case report.Radiology case reports · 2026Article
- Successful Retrieval of a Pathologically Proven Calcified Thrombus Using Nimbus: A Case Report.Journal of neuroendovascular therapy · 2026Article
- Emergency anterior cerebral artery endarterectomy after mechanical thrombectomy failure: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Clinical and radiological characteristics of calcified cerebral embolism: a large case series including 242 calcified cerebral embolism.Acta neurologica Belgica · 2025Article
- Endovascular Thrombectomy for Acute Ischemic Stroke due to Calcified Cerebral Emboli.Stroke research and treatment · 2025Article
- Histopathological composition of thrombus material in a large cohort of patients with acute ischemic stroke: a study of atypical clots.Frontiers in neurology · 2025Article
- Persistent intracranial steno-occlusion from calcified embolism: a treatment challenge.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Mechanical thrombectomy using the Nimbus stent-retriever - initial experiences in a single-center observational study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Observational
- Aortogenic calcified cerebral embolism diagnosed with an embolus retrieved by thrombectomy: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Spontaneous calcified cerebral emboli: a comprehensive review and proposed diagnostic criteria.Frontiers in neurology · 2024Review
- What is a Challenging Clot? : A DELPHI Consensus Statement from the CLOTS 7.0 Summit.Clinical neuroradiology · 2023Article
- Coronary Angiography Complicated by Acute Ischaemic Stroke and the Use of Thrombolysis: a Cardiology Perspective and Narrative Review of Current Literature.Current cardiology reports · 2023Review
- Ischemic Stroke due to Intracranial Embolization of a Pelvic Phlebolith in a Pregnant Patient Successfully Treated by Surgical Embolectomy following Attempted Endovascular Thrombectomy.Case reports in radiology · 2023Article
- Clot Morphology in Acute Ischemic Stroke Decision Making.International journal of molecular sciences · 2022Review
- Acute Calcific Cerebral Embolism Large Vessel Occlusion: A Unique Stroke Mechanism With Hard Challenges.Cureus · 2022Article
- Review
- Reasons for Failed Mechanical Thrombectomy in Posterior Circulation Ischemic Stroke Patients.Clinical neuroradiology · 2021Article
- Refractory Stroke Thrombectomy: Prevalence, Etiology, and Adjunctive Treatment in a North American Cohort.AJNR. American journal of neuroradiology · 2021Article
- Unmet Needs in Acute Ischemic Stroke: Overcoming Recalcitrant Clots.Cardiology in reviewReview
Corrections and comments
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Authors and funding
15 authors at 9 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeLarge intracranial vessel occlusion due to calcified emboli is a rare cause of major stroke. We assessed the prevalence, imaging appearance, the effectiveness of mechanical thrombectomy, and clinical outcome of patients with large-vessel occlusion due to calcified emboli. MATERIALS AND
methodsWe performed a retrospective analysis of clinical and procedural data of consecutive patients who underwent mechanical thrombectomy due to calcified emboli in 7 European stroke centers.
resultsWe screened 2969 patients, and 40 patients matched the inclusion criteria, accounting for a prevalence of 1.3%. The mean maximal density of the thrombus was 327 HU (range, 150-1200 HU), and the mean thrombus length was 9.2 mm (range, 4-20 mm). Four patients had multiple calcified emboli, and 2 patients had an embolic event during an endovascular intervention. A modified TICI score of ≥2b was achieved in 57.5% (23/40), with minimal-to-no reperfusion (modified TICI 0-1) in 32.5% (13/40) and incomplete reperfusion (modified TICI 2a) in 10% (4/40). Excellent outcome (mRS 0-1) was achieved in only 20.6%, functional independence (mRS 0-2) in 26.5% and 90-day mortality was 55.9%.
conclusionsAcute ischemic stroke with large-vessel occlusion due to calcified emboli is a rare entity in patients undergoing thrombectomy, with considerably worse angiographic outcome and a higher mortality compared with patients with noncalcified thrombi. Good functional recovery at 3 months can still be achieved in about a quarter of patients.
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