Evidence map›Paper›PMID 32029469›Full record

ArticleAJNR. American journal of neuroradiology2020

Value of Endolymphatic Hydrops and Perilymph Signal Intensity in Suspected Ménière Disease.

J M van Steekelenburg, A van Weijnen, L M H de Pont, O D Vijlbrief, C C Bommeljé, J P Koopman, B M Verbist, H M Blom, S Hammer

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
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  3. Potential Application of Hydrops MR Imaging: A Systematic Review.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Pooled it
  4. Frequency- and time-dependent hearing improvement after glycerol administration in suspected Ménière's disease: a secondary analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  9. Correlation of endolymphatic hydrops with clinical characteristics in patients with unilateral Ménière's disease.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  10. Comparison of gadolinium-enhanced MRI of the inner ear with definite Meniere's disease in the detection of endolymphatic hydrops between intratympanic and intravenous injection.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

J M van SteekelenburgFrom the Departments of Radiology (J.M.v.S., L.M.H.d.P., S.H.) j.vansteekelenburg@hagaziekenhuis.nl.ORCID 0000-0003-3360-1972
A van WeijnenOtorhinolaryngology (A.v.W., C.C.B., J.P.K., H.M.B.), Haga Teaching Hospital, The Hague, the Netherlands.ORCID 0000-0003-2798-9771
L M H de PontFrom the Departments of Radiology (J.M.v.S., L.M.H.d.P., S.H.).ORCID 0000-0001-7640-7630
O D VijlbriefDepartment of Radiology (O.D.V.), Ziekenhuis Groep Twente, Almelo, the Netherlands.ORCID 0000-0003-2303-6009
C C BommeljéOtorhinolaryngology (A.v.W., C.C.B., J.P.K., H.M.B.), Haga Teaching Hospital, The Hague, the Netherlands.ORCID 0000-0001-7227-6629
J P KoopmanOtorhinolaryngology (A.v.W., C.C.B., J.P.K., H.M.B.), Haga Teaching Hospital, The Hague, the Netherlands.ORCID 0000-0002-5807-3443
B M VerbistDepartment of Radiology (B.M.V.), Leiden University Medical Centre, Leiden, the Netherlands.ORCID 0000-0002-1010-2583
H M BlomOtorhinolaryngology (A.v.W., C.C.B., J.P.K., H.M.B.), Haga Teaching Hospital, The Hague, the Netherlands.ORCID 0000-0002-6075-9647
S HammerFrom the Departments of Radiology (J.M.v.S., L.M.H.d.P., S.H.).ORCID 0000-0002-1576-1190
Haga Hospital · NLMaine Farmland Trust · USJuliana Kinderziekenhuis · NLLeiden University · NLZiekenhuis Groep Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMénière disease is characterized by endolymphatic hydrops, whereas perilymphatic enhancement on MR imaging has been suggested to be of additional value in diagnosing Ménière disease. This study evaluates the presence of endolymphatic hydrops and perilymphatic enhancement in patients with Ménière disease and with other vertigo-associated inner ear pathology. MATERIALS AND

methodsA 3D-FLAIR sequence 4 hours after intravenous gadolinium injection was performed to visualize the endolymph and perilymph in 220 patients suspected of having Ménière disease. Patients' ears were retrospectively categorized as having Ménière disease (probable or definite) or other vertigo-associated inner ear pathology not attributable to Ménière disease. Endolymphatic hydrops was evaluated using a visual classification system, and perilymphatic enhancement was scored both visually and quantitatively.

resultsEndolymphatic hydrops was present in 137 (91.9%) of the definite Ménière disease ears and in 9 (7.0%) of the ears with other vertigo-associated inner ear pathology (

conclusionsThe combination of perilymphatic enhancement and endolymphatic hydrops in patients suspected of having Ménière disease increases the positive predictive value in the diagnosis of definite Ménière disease.

Indexed as

AdultAgedAged, 80 and overEndolymphatic HydropsFemaleGadolinium DTPAHumansMagnetic Resonance ImagingMaleMeniere DiseaseMiddle AgedPerilymphPredictive Value of TestsRetrospective StudiesGadolinium DTPA

Identifiers

PMID32029469
PMCPMC7077918
OpenAlexW3005313486

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.