Evidence map›Paper›PMID 32029004›Full record

GuidelineMilitary Medical Research2020

A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version).

Ying-Hui Jin, Lin Cai, Zhen-Shun Cheng, Hong Cheng, Tong Deng, Yi-Pin Fan, Cheng Fang, Di Huang, Lu-Qi Huang, Qiao Huang and 37 more

3 registry-linked trialsOpen access · diamondAbstract readPractice Guideline
In one paragraph

Guideline in Military Medical Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 1,067 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,067citing papers in PubMed, 10 pooled it
57.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04273529 phase2unknown statusnot on this map

The Efficacy and Safety of Thalidomide in the Adjuvant Treatment of Moderate New Coronavirus (COVID-19) Pneumonia: a Prospective, Multicenter, Randomized, Double-blind, Placebo, Parallel Controlled Clinical Study

TypeinterventionalSponsorFirst Affiliated Hospital of Wenzhou Medical UniversityRan2020 to 2020Enrolled100ConditionsCOVID-19 ThalidomideArmsthalidomide, placebo
NCT04273581 phase2unknown statusnot on this map

The Efficacy and Safety of Thalidomide Combined With Low-dose Hormones in the Treatment of Severe New Coronavirus (COVID-19) Pneumonia: a Prospective, Multicenter, Randomized, Double-blind, Placebo, Parallel Controlled Clinical Study

TypeinterventionalSponsorFirst Affiliated Hospital of Wenzhou Medical UniversityRan2020 to 2020Enrolled40ConditionsCOVID-19 ThalidomideArmsplacebo, Thalidomide
NCT04978051 phase2completednot on this mapstarted 2021, after this paper: background citation

Randomized, Open, Multicenter Phase II Clinical Trial, Proof of Concept, to Evaluate Efficacy and Safety of Icatibant in Hospitalized Patients With SARS-COV-2 (COVID-19) Without Assisted Ventilation Compared With Standard Care

TypeinterventionalSponsorSebastian VidelaRan2021 to 2022Enrolled73ConditionsCOVID-19 PneumoniaArmsFirazyr, SoC
3 · Its place in the literature

Who cites it

1,067 citing papers in PubMed, 10 syntheses or guidelines pooled it, 2,356 citations in OpenAlex.

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  11. Colchicine reduces the activation of NLRP3 inflammasome in COVID-19 patients.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Trial
  12. Effectiveness of Liu-zi-jue exercise on coronavirus disease 2019 in the patients: a randomized controlled trial.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2022
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  13. Trial
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  15. Article
  16. Performance of AI Approaches for COVID-19 Diagnosis Using Chest CT Scans: The Impact of Architecture and Dataset.RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2026
    Article
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1,007 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

47 authors at 4 institutions in 2 countries.

Ying-Hui JinCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Lin CaiInstitute of Hospital Management, Wuhan University, Wuhan, 430071, China.
Zhen-Shun ChengDepartment of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Hong ChengDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Tong DengCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yi-Pin FanChina Academy of Chinese Medical Sciences, Beijing, 100700, China.
Cheng FangCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Di HuangCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Lu-Qi HuangChina Academy of Chinese Medical Sciences, Beijing, 100700, China.
Qiao HuangCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yong HanInstitute of Hospital Management, Wuhan University, Wuhan, 430071, China.
Bo HuDepartment of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Fen HuDepartment of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Bing-Hui LiCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yi-Rong LiDepartment of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Ke LiangDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Li-Kai LinInstitute of Hospital Management, Wuhan University, Wuhan, 430071, China.
Li-Sha LuoCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Jing MaDepartment of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Lin-Lu MaCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Zhi-Yong PengDepartment of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yun-Bao PanDepartment of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Zhen-Yu PanDivision of Medical Affairs, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Xue-Qun RenInstitute of Evidence-Based Medicine and Knowledge Translation, Henan University, Kaifeng, 475000, China.
Hui-Min SunDivision of Nursing Affairs, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Ying WangOffice of Nosocomial Infection Control, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yun-Yun WangCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Hong WengCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Chao-Jie WeiDepartment of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Dong-Fang WuDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Jian XiaEmergency Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yong XiongDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Hai-Bo XuDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Xiao-Mei YaoDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, L8S 4L8, Canada.
Yu-Feng YuanInstitute of Hospital Management, Wuhan University, Wuhan, 430071, China.
Tai-Sheng YeDepartment of Traditional Chinese Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Xiao-Chun ZhangDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Ying-Wen ZhangDepartment of Traditional Chinese Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Yin-Gao ZhangInstitute of Hospital Management, Wuhan University, Wuhan, 430071, China.
Hua-Min ZhangChina Academy of Chinese Medical Sciences, Beijing, 100700, China.
Yan ZhaoEmergency Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Ming-Juan ZhaoCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Hao ZiCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Xian-Tao ZengCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. zengxiantao1128@163.com.
Yong-Yan WangChina Academy of Chinese Medical Sciences, Beijing, 100700, China. wangyyanpublic@bta.net.cn.
Xing-Huan WangCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. wangxinghuan1965@163.com.
, for the Zhongnan Hospital of Wuhan University Novel Coronavirus Management and Research Team, Evidence-Based Medicine Chapter of China International Exchange and Promotive Association for Medical and Health Care (CPAM)
Wuhan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNHenan University · CNImpact · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named "2019 novel coronavirus (2019-nCoV)" by the World Health Organization (WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world's attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development; we also added the first-hand management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control (including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV.

Indexed as

BetacoronavirusCoronavirus InfectionsCross InfectionInfection ControlMass ScreeningPersonal Protective EquipmentPneumonia, ViralAnti-Bacterial AgentsAntiviral AgentsClinical Laboratory TechniquesCOVID-19COVID-19 Drug TreatmentCOVID-19 TestingDiagnosis, DifferentialDrugs, Chinese HerbalEvidence-Based MedicineAnti-Bacterial AgentsAntiviral AgentsDrugs, Chinese Herbal2019-nCoV2019 novel coronavirusClinical practice guidelineEvidence-based medicineInfectious diseasesPneumoniaRapid advice guidelineRespiratory disease

Identifiers

PMID32029004
PMCPMC7003341
OpenAlexW3004824173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.