ArticleBMC pulmonary medicine2020
Pulmonary alveolar proteinosis in Korea: analysis of prevalence and incidence via a nationwide population-based study.
Article in BMC pulmonary medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- A Multicenter Registry for Rare Interstitial Lung Diseases in Korea: Baseline Characteristics and Clinical Outcomes.Tuberculosis and respiratory diseases · 2026Article
- Occupational exposures and risk of pulmonary alveolar proteinosis (PAP).Scandinavian journal of work, environment & health · 2026Article
- Epidemiology of pulmonary alveolar proteinosis: a descriptive study using a Japanese national administrative claims database.ERJ open research · 2025Article
- Complete remission of pulmonary alveolar proteinosis after anti-tuberculous chemotherapy: a case report.The Journal of international medical research · 2022Article
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4 authors.
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Abstract
backgroundPulmonary alveolar proteinosis (PAP) is a very rare lung disease and its prevalence and incidence remain unclear. The prevalence and incidence of PAP were investigated by using nationwide claims data from the Korean Health Insurance Review and Assessment service.
methodsData were extracted for adults who visited any secondary or tertiary medical institute between 2010 and 2016 with the PAP-related Korean Classification of Disease, 7th edition code J84.0 and the Rare Intractable Disease exempted calculation code V222. To robust case definition, a narrow case definition was made when all following factors were met: 1) more than two PAP-coded visits within 1 year of the first claim, and 2) more than one claim for both chest computed tomography and diagnostic procedures (bronchoscopy or surgical lung biopsy) within 90 days before or after the first claim.
resultsA total of 182 patients (narrow, n = 82) with PAP-related codes were identified from 2010 to 2016 and 89 new patients (narrow, n = 66) visited medical institutes between 2012 and 2015. The prevalence of PAP was 4.44 (narrow: 2.27) per 10
conclusionsThe prevalence and incidence of PAP in Korea are low, similar to those in other countries; however, Korean patients with PAP are characterized by older diagnostic age and a lower male-to-female ratio.
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