ArticleMaterials (Basel, Switzerland)2020
A BODIPY-Based Fluorogenic Probe for Specific Imaging of Lipid Droplets.
Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed.
- 3D Hydrogel Culture System Recapitulates Key Tuberculosis Phenotypes and Demonstrates Pyrazinamide Efficacy.Advanced healthcare materials · 2025Article
- Self-Assembled BODIPY Nanoparticles for Near-Infrared Fluorescence Bioimaging.Molecules (Basel, Switzerland) · 2023Article
- Solvatochromic Sensitivity of BODIPY Probes: A New Tool for Selecting Fluorophores and Polarity Mapping.International journal of molecular sciences · 2023Article
- The Role of Cytosolic Lipid Droplets in Hepatitis C Virus Replication, Assembly, and Release.BioMed research international · 2023Review
- Tuning Photodynamic Properties of BODIPY Dyes, Porphyrins' Little Sisters.Molecules (Basel, Switzerland) · 2021Article
- Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice.Learning & memory (Cold Spring Harbor, N.Y.) · 2020Article
- Coordination Polymers Based on Highly Emissive Ligands: Synthesis and Functional Properties.Materials (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed an easily accessible boron-dipyrromethene (BODIPY)-based fluorogenic probe, which we named LD-TB. This probe emits bright fluorescence in oil; when compared with aqueous solution, a significant enhancement of fluorescence brightness is observed. Cellular experiments confirmed that the probe stains the lipid droplets (LDs) specifically in both live and fixed cells, providing background-free images. Compared with Nile Red dye, a commonly used LD marker, LD-TB showed superior photostability. The sharp absorption and emission bands enable its multicolor imaging with blue and green probes. Importantly, the probe has proved to have low toxicity and is compatible with cell fixation. Our research provides a promising new fluorogenic probe for specific imaging of LDs.
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Registered trials
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