ArticleSensors (Basel, Switzerland)2020
Immunosensor Based on Long-Period Fiber Gratings for Detection of Viruses Causing Gastroenteritis.
Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- Engineered Protein Modification: A New Paradigm for Enhancing Biosensing Sensitivity and Diagnostic Accuracy.Biosensors · 2025Review
- Sensitive Electrochemical and Thermal Detection of Human Noroviruses Using Molecularly Imprinted Polymer Nanoparticles Generated against a Viral Target.ACS applied materials & interfaces · 2024Article
- Non-spherical gold nanoparticles enhanced fluorescence of carbon dots for norovirus-like particles detection.Journal of biological engineering · 2023Article
- Binding of SARS-CoV-2 Structural Proteins to Hemoglobin and Myoglobin Studied by SPR and DR LPG.Sensors (Basel, Switzerland) · 2023Article
- Capabilities of Double-Resonance LPG and SPR Methods for Hypersensitive Detection of SARS-CoV-2 Structural Proteins: A Comparative Study.Biosensors · 2023Article
- Long-Period Fiber Grating Sensors for Chemical and Biomedical Applications.Sensors (Basel, Switzerland) · 2023Review
- SARS-CoV-2 spike protein detection using slightly tapered no-core fiber-based optical transducer.Mikrochimica acta · 2022Article
- Differential Refractometric Biosensor for Reliable Human IgG Detection: Proof of Concept.Biosensors · 2022Article
- Recent Advances in Early Diagnosis of Viruses Associated with Gastroenteritis by Biosensors.Biosensors · 2022Review
- Immunization with Leishmania tarentolae-derived norovirus virus-like particles elicits high humoral response and stimulates the production of neutralizing antibodies.Microbial cell factories · 2021Article
- Immunosensing Based on Optical Fiber Technology: Recent Advances.Biosensors · 2021Review
- Portable Sensing Devices for Detection of COVID-19: A Review.IEEE sensors journal · 2021Article
- An Analysis Review of Detection Coronavirus Disease 2019 (COVID-19) Based on Biosensor Application.Sensors (Basel, Switzerland) · 2020Review
- Analysis of Long Period Gratings Inscribed by COSensors (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Since the norovirus is the main cause of acute gastroenteritis all over the world, its fast detection is crucial in medical diagnostics. In this work, a rapid, sensitive, and selective optical fiber biosensor for the detection of norovirus virus-like particles (VLPs) is reported. The sensor is based on highly sensitive long-period fiber gratings (LPFGs) coated with antibodies against the main coat protein of the norovirus. Several modification methods were verified to obtain reliable immobilization of protein receptors on the LPFG surface. We were able to detect 1 ng/mL norovirus VLPs in a 40-min assay in a label-free manner. Thanks to the application of an optical fiber as the sensor, there is a possibility to increase the user's safety by separating the measurement point from the signal processing setup. Moreover, our sensor is small and light, and the proposed assay is straightforward. The designed LPFG-based biosensor could be applied in both fast norovirus detection and in vaccine testing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.