Evidence map›Paper›PMID 32028263›Full record

ArticleAging2020

Methionine increases yolk production to offset the negative effect of caloric restriction on reproduction without affecting longevity in

Gaojian Zhou, Chuan Huang, Liu Xing, Le Li, Yan Jiang, Yuehua Wei

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Gaojian ZhouBasic Medicine College, Central South University, Changsha, Hunan, People's Republic of China.
Chuan HuangReproductive and Genetic Hospital of CITIC-Xiangya, Changsha, Hunan, People's Republic of China.
Liu XingReproductive and Genetic Hospital of CITIC-Xiangya, Changsha, Hunan, People's Republic of China.
Le LiProMab Biotechnologies, Richmond, CA 94806, USA.
Yan JiangHunan Gaocell Medical Technology Co. Ltd., Changsha, Hunan, People's Republic of China.
Yuehua WeiShanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, People's Republic of China.
Reproductive & Genetic Hospital CITIC-Xiangya · CNCentral South University · CNPromega (United States) · USShanghai Ninth People's Hospital · CN

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Caloric restriction (CR) or Dietary restriction (DR) is known to improve health and in many cases increases lifespan. However, its negative effect on reproduction has not been fully studied. Practicing CR/DR without adequate knowledge on its side effect may risk complications such as infertility, birth defect, or malnutrition. In this study, by using several CR strategies in

Indexed as

Dietary SupplementsEnergy IntakeLongevityAnimalsCaenorhabditis elegansEgg YolkMethionineMethioninecalorie restriction (CR)methioninereproductionside effectvitellogenin

Identifiers

PMID32028263
PMCPMC7041781
OpenAlexW3005343541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.