Evidence map›Paper›PMID 32027799›Full record

ArticleJournal of stroke2020

Hospital Volume Threshold Associated with Higher Survival after Endovascular Recanalization Therapy for Acute Ischemic Stroke.

Dong-Hyun Shim, Youngsoo Kim, Jieun Roh, Jongsoo Kang, Kyung-Pil Park, Jae-Kwan Cha, Seung Kug Baik, Yoon Kim

Registry-linked trialAbstract read
In one paragraph

Article in Journal of stroke, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05817097 (Effect of Dipeptidyl-4 Inhibitors in Reducing Stroke Severity, From the Health Insurance Review and Assessment Service Database), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05817097 unknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Dipeptidyl-4 Inhibitors in Reducing Stroke Severity, From the Health Insurance Review and Assessment Service Database

TypeobservationalSponsorAjou University School of MedicineRan2023 to 2024Enrolled22,119ConditionsCerebral Infarction, Infarction, Brain, Dipeptidyl-Peptidase IV InhibitorsArmsDipeptidyl peptidase-4 inhibitor
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
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  6. Thrombectomy-capable vs. comprehensive stroke centers: impact on endovascular therapy outcomes in acute large vessel occlusion.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  7. Article
  8. Association of endovascular thrombectomy volume and outcomes in acute ischemic stroke: A National Inpatient Sample Study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Annual Endovascular Thrombectomy Case Volume and Thrombectomy-capable Hospitals of Korea in Acute Stroke Care.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dong-Hyun ShimDepartment of Neurology, Kyungpook National University Hospital, Daegu, Korea.
Youngsoo KimDepartment of Neurosurgery, MH Yeonse Hospital, Changwon, Korea.
Jieun RohDepartment of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Jongsoo KangDepartment of Neurology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.
Kyung-Pil ParkDepartment of Neurology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Jae-Kwan ChaDepartment of Neurology, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea.
Seung Kug BaikDepartment of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Yoon KimDepartment of Health Policy and Management, Seoul National University College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeEndovascular recanalization therapy (ERT) is becoming increasingly important in the management of acute ischemic stroke (AIS). However, the hospital volume threshold for optimal ERT remains unknown. We investigated the relationship between hospital volume of ERT and risk-adjusted patient outcomes.

methodsFrom the National Health Insurance claims data in Korea, 11,745 patients with AIS who underwent ERT from July 2011 to June 2016 in 111 hospitals were selected. We measured the hospital's ERT volume and patient outcomes, including the 30-day mortality, readmission, and postprocedural intracranial hemorrhage (ICH) rates. For each outcome measure, we constructed risk-adjusted prediction models incorporating demographic variables, the modified Charlson comorbidity index, and the stroke severity index (SSI), and validated them. Risk-adjusted outcomes of AIS cases were compared across hospital quartiles to confirm the volume-outcome relationship (VOR) in ERT. Spline regression was performed to determine the volume threshold.

resultsThe mean AIS volume was 14.8 cases per hospital/year and the unadjusted means of mortality, readmission, and ICH rates were 11.6%, 4.6%, and 8.6%, respectively. The VOR was observed in the risk-adjusted 30-day mortality rate across all quartile groups, and in the ICH rate between the first and fourth quartiles (P<0.05). The volume threshold was 24 cases per year.

conclusionsThere was an association between hospital volume and outcomes, and the volume threshold in ERT was identified. Policies should be developed to ensure the implementation of the AIS volume threshold for hospitals performing ERT.

Indexed as

Hospitals, high-volumeQuality and outcomesRisk adjustmentStrokeThrombectomy

Identifiers

PMID32027799
PMCPMC7005355

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.