ReviewJournal of stroke2020
Pathophysiologic and Therapeutic Perspectives Based on Thrombus Histology in Stroke.
Review in Journal of stroke, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed.
- Stroke Recurrence and Long-Term Mortality in Patients Diagnosed with Cancer Following Stroke.Yonsei medical journal · 2026Observational
- Evolution of neutrophil extracellular traps in the pathology of stroke.Neural regeneration research · 2026Article
- Different Long-Term Outcomes According to Thrombus Histology in Patients With Acute Ischemic Stroke.Journal of stroke · 2026Article
- Neurovascular Unit-Derived Extracellular Vesicles as Regulators of Post-Stroke Pathology and Neurorestoration.Biomolecules · 2026Review
- The immunothrombosis pathway linking pulmonary disease to stroke and neurodegeneration: mechanisms and therapeutic implications.Frontiers in pharmacology · 2026Review
- Detailed Analysis of Thrombus Composition and Endovascular Thrombectomy Efficiency in Ischemic Stroke Patients with Middle Cerebral Artery Occlusion Undergoing Thrombectomy.Journal of clinical medicine · 2025Article
- Risk factors and outcomes of patients with early spontaneous recanalization after acute middle cerebral artery occlusion.Quantitative imaging in medicine and surgery · 2025Article
- Transcriptomic profiling of thrombus-derived extracellular vesicles reveals PECAM-1 as a potential inflammatory marker for cardioembolic stroke patients.Journal of neuroinflammation · 2025Article
- Annexin A5 in Ischemic Stroke: Molecular Mechanisms and Translational Therapy Strategies.Aging and disease · 2025Review
- Thrombus Composition in Cerebral Venous Thrombosis.Stroke research and treatment · 2025Article
- Thrombus composition and distribution patterns by thrombus volume in acute ischemic stroke.Frontiers in neurology · 2025Article
- Multifunctional applications and research advances of low-molecular-weight heparin.Frontiers in pharmacology · 2025Review
- Bathing-Related Ischemic Stroke: Association between Stroke Subtype and Cerebral Small Vessel Disease.Journal of atherosclerosis and thrombosis · 2024Article
- Is Clot Composition Associated With Cause of Stroke? A Systematic Review and Meta-Analysis.Stroke (Hoboken, N.J.) · 2024Article
- Association Between the Timing of Atrial Fibrillation Detection and Functional Outcome Following Mechanical Thrombectomy.Journal of the American Heart Association · 2024Article
- Deep learning prediction of stroke thrombus red blood cell content from multiparametric MRI.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Article
- Traditional Thrombus Composition and Related Endovascular Outcomes: Catching up with the Recent Evidence.Neurointervention · 2024Review
- Cancer-Associated Stroke: Thrombosis Mechanism, Diagnosis, Outcome, and Therapeutic Strategies.Journal of stroke · 2024Review
- Electroacupuncture modulates abnormal brain connectivity after ischemia reperfusion injury in rats: A graph theory-based approach.Brain and behavior · 2024Article
- Multimaterial decomposition in dual-energy CT for characterization of clots from acute ischemic stroke patients.European radiology experimental · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Recent advances in endovascular thrombectomy have enabled the histopathologic analysis of fresh thrombi in patients with acute stroke. Histologic analysis has shown that the thrombus composition is very heterogeneous between patients. However, the distribution pattern of each thrombus component often differs between patients with cardiac thrombi and those with arterial thrombi, and the efficacy of endovascular thrombectomy is different according to the thrombus composition. Furthermore, the thrombus age is related to the efficacy of reperfusion therapy. Recent studies have shown that neutrophils and neutrophil extracellular traps contribute to thrombus formation and resistance to reperfusion therapy. Histologic features of thrombi in patients with stroke may provide some clues to stroke etiology, which is helpful for determining the strategy of stroke prevention. Research on thrombus may also be helpful for improving reperfusion therapy, including the development of new thrombolytic agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.