Evidence map›Paper›PMID 32027538›Full record

ArticleJCO clinical cancer informatics2020

The International Association for the Study of Lung Cancer Early Lung Imaging Confederation.

James L Mulshine, Ricardo S Avila, Ed Conley, Anand Devaraj, Laurie Fenton Ambrose, Tanya Flanagan, Claudia I Henschke, Fred R Hirsch, Robert Janz, Ryutaro Kakinuma and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in JCO clinical cancer informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The radiologist's role in lung cancer screening.Translational lung cancer research · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 19 institutions in 8 countries.

James L MulshineRush University, Chicago, IL.
Ricardo S AvilaAccumetra, LLC, Clifton Park, NY.
Ed ConleyUniversity of Liverpool, Liverpool, United Kingdom.
Anand DevarajUniversity College, London, United Kingdom.
Laurie Fenton AmbroseGO2 Foundation, Washington, DC.
Tanya FlanaganPartnership Against Cancer, Toronto, Ontario, Canada.
Claudia I HenschkeIcahn School of Medicine at Mount Sinai, New York, NY.
Fred R HirschMount Sinai Health System, New York, NY.
Robert JanzUniversity of Groningen, Groningen, Netherlands.
Ryutaro KakinumaNational Cancer Center Hospital, Tokyo, Japan.
Stephen LamUniversity of British Columbia, Vancouver, British Columbia, Canada.
Annette McWilliamsFiona Stanley Hospital, Western Australia.
Peter M A Van OoijenUniversity Medical College, Groningen, Netherlands.
Matthijs OudkerkUniversity Medical College, Groningen, Netherlands.
Ugo PastorinoInstituti Tumori, Milan, Italy.
Anthony ReevesCornell University, Ithaca, New York, NY.
Patrick RogallaToronto Joint Department of Medical Imaging, University of Toronto, Ontario, Canada.
Heidi SchmidtToronto Joint Department of Medical Imaging, University of Toronto, Ontario, Canada.
Daniel C SullivanDuke University Medical Center, Durham, NC.
Haije H J WindUniversity Medical College, Groningen, Netherlands.
Ning WuNational Cancer Center, Peking Union Medical College, Beijing, China.
Murry WynesInternational Association for the Study of Lung Cancer, Denver, CO.
Xie XueqianShanghai General Hospital, Shanghai, China.
David F YankelevitzIcahn School of Medicine at Mount Sinai, New York, NY.
John K FieldUniversity of Liverpool, Liverpool, United Kingdom.
University Medical Center Groningen · NLIcahn School of Medicine at Mount Sinai · USUniversity of Liverpool · GBUniversity of Toronto · CACanadian Partnership Against Cancer · CAChinese Academy of Medical Sciences & Peking Union Medical College · CNCornell University · USDuke Medical Center · USFiona Stanley Hospital · AUFondazione IRCCS Istituto Nazionale dei Tumori · ITGo2 for Lung Cancer · USInternational Association for the Study of Lung Cancer · USMount Sinai Health System · USRush University · USShanghai First People's Hospital · CNTokyo National Hospital · JPUniversity College London · GBUniversity of British Columbia · CAUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo improve outcomes for lung cancer through low-dose computed tomography (LDCT) early lung cancer detection. The International Association for the Study of Lung Cancer is developing the Early Lung Imaging Confederation (ELIC) to serve as an open-source, international, universally accessible environment to analyze large collections of quality-controlled LDCT images and associated biomedical data for research and routine screening care.

methodsELIC is an international confederation that allows access to efficiently analyze large numbers of high-quality computed tomography (CT) images with associated de-identified clinical information without moving primary imaging/clinical or imaging data from its local or regional site of origin. Rather, ELIC uses a cloud-based infrastructure to distribute analysis tools to the local site of the stored imaging and clinical data, thereby allowing for research and quality studies to proceed in a vendor-neutral, collaborative environment. ELIC's hub-and-spoke architecture will be deployed to permit analysis of CT images and associated data in a secure environment, without any requirement to reveal the data itself (ie, privacy protecting). Identifiable data remain under local control, so the resulting environment complies with national regulations and mitigates against privacy or data disclosure risk.

resultsThe goal of pilot experiments is to connect image collections of LDCT scans that can be accurately analyzed in a fashion to support a global network using methodologies that can be readily scaled to accrued databases of sufficient size to develop and validate robust quantitative imaging tools.

conclusionThis initiative can rapidly accelerate improvements to the multidisciplinary management of early, curable lung cancer and other major thoracic diseases (eg, coronary artery disease and chronic obstructive pulmonary disease) visualized on a screening LDCT scan. The addition of a facile, quantitative CT scanner image quality conformance process is a unique step toward improving the reliability of clinical decision support with CT screening worldwide.

Indexed as

AlgorithmsEarly Detection of CancerHumansImage Processing, Computer-AssistedLung NeoplasmsPatient SelectionPractice Guidelines as TopicReproducibility of ResultsTomography, X-Ray Computed

Identifiers

PMID32027538
PMCPMC7053806
OpenAlexW3005439854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.