Evidence map›Paper›PMID 32027394›Full record

ArticleTransfusion2020

How do you… decide which platelet bacterial risk mitigation strategy to select for your hospital-based transfusion service?

Wen Lu, Meghan Delaney, Willy A Flegel, Paul Ness, Nora Ratcliffe, Darrell J Triulzi, Mark H Yazer, Alyssa Ziman, Nancy M Dunbar

Abstract read
In one paragraph

Article in Transfusion, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Pathogen-reduction technology, good in more than one way for cellular blood components, is replacing irradiation.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wen LuRobert Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.ORCID 0000-0003-2292-3167
Meghan DelaneyPathology and Laboratory Medicine, Children's National Medical Center, Washington, DC.
Willy A FlegelDepartment of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0002-1631-7198
Paul NessDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Nora RatcliffePathology & Laboratory Medicine, White River Junction VA Medical Center, White River Junction, Vermont.
Darrell J TriulziCentralized Transfusion Service, University of Pittsburgh, Pittsburgh, Pennsylvania.
Mark H YazerCentralized Transfusion Service, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0001-5937-3301
Alyssa ZimanWing-Kwai and Alice Lee-Tsing Chung Transfusion Service, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
Nancy M DunbarDepartment of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire.ORCID 0000-0001-8601-5438

Funding

CLC NIH HHS Z99 CL999999Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

The United States Food and Drug Administration Final Guidance for Industry titled, "Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion" provides nine strategies for platelet bacterial risk mitigation. Even if it is assumed all strategies are comparable in terms of safety and efficacy, the decision of which to implement remains challenging. Some additional factors that warrant evaluation before selecting a strategy include the financial impact, process for implementation, logistics upon implementation, institutional acceptance by blood bank staff, administration and clinicians, and effect on platelet availability. To assist with this difficult choice, a panel of transfusion service physicians who have expertise on the topic and have already selected strategies for their transfusion services were recruited to provide varied perspectives. In addition, the use of a decision-making tool that objectively evaluates defined criteria for assessment of the nine strategies is described.

Indexed as

Decision MakingHospitalsAlgorithmsBacteriaBlood BankingBlood PlateletsHumansPlatelet TransfusionRiskUnited States

Identifiers

PMID32027394
PMCPMC7131880

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.