ArticleCancer medicine2020
Nomogram for predicting overall survival in stage II-III colorectal cancer.
Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Relation of Mean Platelet Volume (MPV) with Cancer: A Systematic Review with a Focus on Disease Outcome on Twelve Types of Cancer.Current oncology (Toronto, Ont.) · 2023Pooled it
- Intraductal papillary carcinoma of breast with invasion: A nomogram and survival from the analysis of the SEER database.Cancer medicine · 2023Trial
- Development of multi-algorithm machine learning models integrating novel serum biomarkers for survival prediction in colorectal cancer: a retrospective cohort study.Frontiers in oncology · 2026Article
- Construction of a prognostic model for colorectal cancer liver metastasis: A retrospective study based on population data.World journal of gastrointestinal oncology · 2025Article
- Development and Validation of Platelet-Index Based Colorectal Cancer Survival Prognostic Nomogram.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Mean Platelet Volume Is a Poor Prognostic Factor in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025Article
- Construction of a Nomogram Model for Predicting Prognosis in Breast Cancer Patients Based on the Expression of THRSP and ACACA Proteins Tissues.Pharmacogenomics and personalized medicine · 2025Article
- Utilizing tumor deposit count as a stratification criterion in revising TNM staging system for patients with colorectal cancer: a nomogram review study.Frontiers in oncology · 2025Article
- Establishment and Validation of a Prognostic Nomogram for Predicting Postoperative Overall Survival in Advanced Stage III-IV Colorectal Cancer Patients.Cancer medicine · 2024Article
- Analysis of prognostic factors and construction of prognostic models for invasive lobular carcinoma of the breast.Biomolecules & biomedicine · 2024Article
- Article
- Varying clinical relevance of sarcopenia and myosteatosis according to age among patients with postoperative colorectal cancer.The journal of nutrition, health & aging · 2024Article
- Conditional survival analysis and real-time prognosis prediction in stage III T3-T4 colon cancer patients after surgical resection: a SEER database analysis.International journal of colorectal disease · 2024Article
- A prognostic nomogram integrating carcinoembryonic antigen levels for predicting overall survival in elderly patients with stage II-III colorectal cancer.Journal of gastrointestinal oncology · 2024Article
- Construction of prognostic nomogram based on the SEER database for esophageal cancer patients.Clinics (Sao Paulo, Brazil) · 2024Article
- Comparison of intracorporeal and extracorporeal anastomosis in left hemicolectomy: updated meta-analysis of retrospective control trials.Journal of cancer research and clinical oncology · 2023Review
- Construction and validation of a prognostic nomogram for predicting cancer-specific survival in patients with intermediate and advanced colon cancer after receiving surgery and chemotherapy.Journal of cancer research and clinical oncology · 2023Article
- Construction and validation of a nomogram model for predicting the overall survival of colorectal cancer patients.BMC surgery · 2023Article
- Elderly patients over 80 years undergoing colorectal cancer resection: Development and validation of a predictive nomogram for survival.World journal of gastrointestinal surgery · 2023Article
- Dynamic Nomogram for Predicting Long-Term Survival in Terms of Preoperative and Postoperative Radiotherapy Benefits for Advanced Gastric Cancer.International journal of environmental research and public health · 2023Article
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe overall survival (OS) of patients diagnosed with stage II-III colorectal cancer (CRC) can vary greatly, even between patients with the same tumor stage. We aimed to design a nomogram to predict OS in resected, stage II-III CRC and stratify patients with CRC into different risk groups. PATIENTS AND
methodsBased on data from 873 patients with CRC, we used univariate Cox regression analysis to select the significant prognostic features, which were subjected to the least absolute shrinkage and selection operator (LASSO) regression algorithm for feature selection. Cross-validation was used to confirm suitable tuning parameters (λ) for LASSO logistic regression. Then, the nomogram was used to estimate 3- and 5-year OS based on the multivariable Cox regression model. The survival curves of the two groups were produced using the Kaplan-Meier method. Risk group stratification was performed to assess the predictive capacity of the nomogram.
resultsPreoperative mean platelet volume, preoperative platelet distribution width, monocytes, and postoperative adjuvant chemotherapy were identified as independent prognostic factors by LASSO regression and integrated for the construction of the nomogram. The nomogram provided good discrimination, with C-indices of 0.67 and 0.69 for the training and validation sets, respectively. Calibration plots illustrated excellent agreement between the nomogram predictions and actual observations for 3- and 5-year OS. Moreover, a significant difference in OS was shown between patients stratified into different risk groups (P < .001).
conclusionWe constructed and validated an original predictive nomogram for OS in patients with CRC after surgery, facilitating physicians to appraise the individual survival of postoperative patients accurately and identify high-risk patients who need more aggressive treatment and follow-up strategies.
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