Evidence map›Paper›PMID 32026992›Full record

ArticleCVIR endovascular2019

Transcatheter embolization with Squid, combined with other embolic agents or alone, in different abdominal diseases: a single-center experience in 30 patients.

Massimo Venturini, Carolina Lanza, Paolo Marra, Anna Colarieti, Marta Panzeri, Luigi Augello, Simone Gusmini, Marco Salvioni, Francesco De Cobelli, Alessandro Del Maschio

Open access · goldAbstract read
In one paragraph

Article in CVIR endovascular, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Massimo VenturiniDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy. venturini.massimo@hsr.it.
Carolina LanzaDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Paolo MarraDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Anna ColarietiDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Marta PanzeriDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Luigi AugelloDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Simone GusminiDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Marco SalvioniDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Francesco De CobelliDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
Alessandro Del MaschioDepartment of Radiology, Scientific Institute H S. Raffaele, Via Olgettina 60, 20132, Milan, Italy.
San Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSquid, as Onyx, is an ethylene-vinyl alcohol copolymer (EVOH)-based liquid embolic agent developed for neuroradiologic interventions with poor application in abdominal district. Our aim was to evaluate safety, complications, and efficacy of transcatheter embolization using the two available formulations Squid-18 and 12, in 30 patients affected by different abdominal diseases.

resultsTranscatheter embolization with Squid, combined with other embolic agents, as poly vinyl alcohol (PVA) particles, coils and amplatzer plugs, or alone (type 2 endoleak), was performed in 30 patients, as follows: 10 portal vein embolizations (PVEs), 6 arteriovenous malformations (AVMs), 5 visceral artery aneurysms (VAAs), 4 type 2 endoleaks, 3 preoperative embolizations, 1 acute arterial bleeding, 1 female varicocele. Squid was always administered using dimethyl sulfoxide (DMSO) compatible microcatheters. Technical success, 30-day clinical success and complications were assessed. Technical success was 90%. 3 patients (2 AVMs, 1 VAA) required re-intervention successfully performed in all cases. Major complications, cases of microcatheter entrapment and DMSO-related poor pain control were not recorded. 30-day clinical success was 93.3%: in 2 patients submitted to PVE a sufficient future liver remnant (FLR) hypertrophy was not achieved.

conclusionSquid was successfully used with low complication rate in many abdominal diseases showing a valid embolic action either combined with other embolic agents or alone in type 2 endoleak. The availability of different formulations (Squid-18 and Squid-12) variable for viscosity makes Squid preferable to Onyx as EVOH-based liquid embolic agent, even though comparable studies in different abdominal districts with a larger cohort of patients will be necessary.

Indexed as

Arteriovenous malformationPortal vein embolizationSquidTranscatheter embolizationType 2 endoleakVisceral aneurysm

Identifiers

PMID32026992
PMCPMC6966379
OpenAlexW2921833676

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.